Rat DLC1 Monoclonal Antibody | anti-DLC1 antibody
DLC1 monoclonal antibody (10D6)
Does not cross-react with DLC2
Does not cross-react with DLC2
Shipping: Shipped on Blue Ice
NCBI and Uniprot Product Information
Uniprot Description
LC8: a highly conserved cytoplasmic protein of the dynein light chain family. Cytoplasmic dyneins are large enzyme complexes. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain. Interacts with and inhibits the activity of neuronal nitric oxide synthase (nNOS). A highly conserved protein, showing 92% amino acid similarity with the nematode homolog. Binding of this protein destabilizes the nNOS dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity.
Protein type: Microtubule-binding; Motility/polarity/chemotaxis; Motor
Chromosomal Location of Human Ortholog: 5|5 F
Cellular Component: centrosome; cytoplasm; cytoplasmic dynein complex; cytoskeleton; cytosol; kinetochore; membrane; nucleus; signalosome
Molecular Function: dynein intermediate chain binding; enzyme binding; enzyme inhibitor activity; nitric-oxide synthase regulator activity; protein binding; protein C-terminus binding; protein domain specific binding; protein homodimerization activity
Biological Process: negative regulation of nitric oxide biosynthetic process; negative regulation of phosphorylation
Research Articles on DLC1
Similar Products
Product Notes
The DLC1 dynll1 (Catalog #AAA566331) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The DLC1 monoclonal antibody (10D6) reacts with Human, Mouse Does not cross-react with DLC2 and may cross-react with other species as described in the data sheet. AAA Biotech's DLC1 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Western Blot (WB). Researchers should empirically determine the suitability of the DLC1 dynll1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DLC1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
