Human Growth Arrest and DNA Damage Inducible Protein Gamma ELISA Kit | GADD45gamma elisa kit

Human Growth Arrest and DNA Damage Inducible Protein Gamma ELISA Kit

Cat. Num. AAA56371

• Gene Names: GADD45G; CR6; DDIT2; GRP17; GADD45gamma
• Reactivity: Human
• Synonyms: Growth Arrest and DNA Damage Inducible Protein Gamma; Human Growth Arrest and DNA Damage Inducible Protein Gamma ELISA Kit; GADD45gamma elisa kit

• Reactivity: Human
• Sequence Length: 159

• Assay Type: Quantitative Sandwich
• Detection Range: 1.56ng/ml-50ng/ml
• Sensitivity: 0.1ng/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for GADD45gamma elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used for determine the level of GADD45G (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 5729836
• NCBI GeneID: 10912
• NCBI Accession #: NP_006696.1
• NCBI GenBank Nucleotide #: NM_006705.3
• UniProt Accession #: O95257; Q5VZ87; Q9C076
• Molecular Weight: 17,121 Da
• NCBI Official Full Name: growth arrest and DNA damage-inducible protein GADD45 gamma
• NCBI Official Synonym Full Names: growth arrest and DNA-damage-inducible, gamma
• NCBI Official Symbol: GADD45G
• NCBI Official Synonym Symbols: CR6; DDIT2; GRP17; GADD45gamma
• NCBI Protein Information: growth arrest and DNA damage-inducible protein GADD45 gamma; DDIT-2; GADD45-gamma; gadd-related protein, 17 kD; cytokine-responsive protein CR6; DNA damage-inducible transcript 2 protein
• UniProt Protein Name: Growth arrest and DNA damage-inducible protein GADD45 gamma
• UniProt Gene Name: GADD45G
• UniProt Synonym Gene Names: CR6; DDIT2; DDIT-2
• UniProt Entry Name: GA45G_HUMAN

NCBI Description

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008]

Uniprot Description

GADD45G: Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK. Belongs to the GADD45 family.

Protein type: Nuclear receptor co-regulator; Apoptosis; DNA repair, damage

Chromosomal Location of Human Ortholog: 9q22.1-q22.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding

Biological Process: activation of MAPKK activity; regulation of cell cycle; positive regulation of apoptosis; apoptosis; multicellular organismal development; activation of MAPKKK activity; negative regulation of protein kinase activity; positive regulation of JNK cascade; response to stress; cell differentiation