Rabbit anti-Dog CRP Polyclonal Antibody | anti-CRP antibody

Rabbit anti-Dog CRP

Cat. Num. AAA560460

• Gene Names: CRP; PTX1; MGC88244; MGC149895
• Reactivity: Dog
• Synonyms: CRP; Polyclonal Antibody; Rabbit anti-Dog CRP; Rabbit anti-Dog CRP (C- Reactive Protein); anti-Dog CRP; anti-CRP antibody

• Host: Rabbit
• Reactivity: Dog
• Clonality: Polyclonal
• Form/Format: Whole Serum; Physical State: Liquid

• Application Notes: Rabbit anti CRP gives a single band by IEP and gel diffusion against fluids with high levels of CRP.
• Preservative: 0.1% Sodium Azide
• Procedure: Rabbits located in the USA were immunized with highly purified dog CRP isolated from the serum of dogs with abnormally high CRP. The resulting antiserum was solid phase absorbed with dog serum lacking CRP until it gave a single band with serum containing the acute phase protein.
• Preparation and Storage: Store at 4 degree C.; Shelf Life: 12 months from shipment date

Related Product Information for anti-CRP antibody

Rabbits were immunized with highly purified dog CRP. Antiserum was collected and solid phase adsorbed to ensure specificity by immunoelectrophoresis.

Product Categories/Family for anti-CRP antibody

Dog Protein

NCBI and Uniprot Product Information

• NCBI GI #: 17975775
• NCBI GeneID: 1401
• UniProt Accession #: P02741; Q08AK3; Q8WW75; A8K078; D3DVD9; D3DVE0; Q5VVP7
• Molecular Weight: 25,039 Da
• NCBI Official Full Name: CRP
• NCBI Official Synonym Full Names: C-reactive protein, pentraxin-related
• NCBI Official Symbol: CRP
• NCBI Official Synonym Symbols: PTX1; MGC88244; MGC149895
• NCBI Protein Information: C-reactive protein; pentraxin 1; OTTHUMP00000033307
• UniProt Protein Name: C-reactive protein
• Protein Family: Cryparin
• UniProt Gene Name: CRP
• UniProt Synonym Gene Names: PTX1
• UniProt Entry Name: CRP_HUMAN

NCBI Description

The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq]

Uniprot Description

CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: extracellular space; growth cone; extracellular region; filopodium

Molecular Function: choline binding; protein binding; protein homodimerization activity; low-density lipoprotein receptor binding; complement component C1q binding; low-density lipoprotein binding; virion binding; cholesterol binding; calcium ion binding

Biological Process: protein polymerization; wound healing; defense response to Gram-positive bacterium; response to ethanol; negative regulation of vasodilation; positive regulation of superoxide release; response to lead ion; response to hypoxia; acute-phase response; opsonization; inflammatory response; complement activation, classical pathway; aging