CD155 recombinant protein
Mouse CD155 Recombinant
Purity
>95%, as determined by SDS-PAGE and HPLC
Synonyms
CD155; Mouse CD155 Recombinant; cd-155; PVR; HVED; NECL5; Necl-5; PVS; TAGE4; CD155 recombinant protein
Host
HEk293 Cells
Purity/Purification
>95%, as determined by SDS-PAGE and HPLC
Form/Format
Recombinant mouse PVR (CD155) is supplied as a 0.2 um filtered PBS solution, pH7.2.
Sequence Length
408
Domain
Ig-like C2
Host Note
Optimized DNA sequence encoding extracellular domain of Mouse PVR CD155 including a C-terminal 6His tag was expressed in HEK293 cells.
Endotoxin
Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
Molecular Weight Note
Recombinant mouse PVR (CD155) is a monomer protein consisting of 329 amino acid residue subunits, due to glycosylation migrates as an approximately 55-60 kDa protein on SDS-PAGE.
Preparation and Storage
Recombinant mouse PVR (CD155), as supplied, can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C to -70 degree C for twelve months.
Avoid repeated freeze/thaw cycles.
Avoid repeated freeze/thaw cycles.
Related Product Information for CD155 recombinant protein
hPVR (CD155) is a member of the immunoglobulin (Ig) superfamily, with three linked extracellular Ig-like domains followed by a membrane-spanning domain and a cytoplasmic domain. Although a physiological function for CD155 is unknown, the protein binds specifically to the extracellular matrix component vitronectin (Lange et al., 2001). Transcriptional regulation of the CD155 gene is tightly controlled.
Product Categories/Family for CD155 recombinant protein
References
• dnam-1/CD155 interactions promote cytokine and nk cell-mediated suppression of poorly immunogenic melanoma metastases .J. Immunol., Jan 2010; 184: 902 - 911.
• primary human tumor cells expressing CD155 impair tumor targeting by down-regulating dnam-1 on nk cells .J. Immunol., Oct 2009; 183: 4921 - 4930.
• cd96 interaction with CD155 via its first ig-like domain is modulated by alternative splicing or mutations in distal ig-like domains .J. Biol. Chem., Jan 2009; 284: 2235 - 2244.
• crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses .PNAS, Nov 2008; 105: 18284 - 18289.
• characterization of the new world monkey homologues of human poliovirus receptor CD155 .J. Virol., Jul 2008; 82: 7167 - 7179.
• primary human tumor cells expressing CD155 impair tumor targeting by down-regulating dnam-1 on nk cells .J. Immunol., Oct 2009; 183: 4921 - 4930.
• cd96 interaction with CD155 via its first ig-like domain is modulated by alternative splicing or mutations in distal ig-like domains .J. Biol. Chem., Jan 2009; 284: 2235 - 2244.
• crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses .PNAS, Nov 2008; 105: 18284 - 18289.
• characterization of the new world monkey homologues of human poliovirus receptor CD155 .J. Virol., Jul 2008; 82: 7167 - 7179.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,668 Da
NCBI Official Full Name
poliovirus receptor
UniProt Protein Name
Poliovirus receptor
UniProt Gene Name
Pvr
UniProt Synonym Gene Names
D7Ertd458e
UniProt Entry Name
Q8K094_MOUSE
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Product Notes
The CD155 pvr (Catalog #AAA553308) is a Recombinant Protein produced from HEk293 Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CD155, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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