Rabbit Soluble Guanylyl Cyclase alpha 1 Polyclonal Antibody | anti-Gucy1a3 antibody
Guanylyl Cyclase alpha 1 Antibody BIOTIN
Immunoprecipitation: 1:200
Western Blot: 1:500
NCBI and Uniprot Product Information
NCBI Description
soluble guanylate cyclase subunit that forms a heterodimer with Gucy1b3; may also function as an intracellular nitric oxide receptor [RGD, Feb 2006]
Uniprot Description
GUCY1A3: Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Protein type: Lyase; EC 4.6.1.2; Nucleotide Metabolism - purine; Receptor, misc.; Guanylyl cyclase
Cellular Component: cytosol; guanylate cyclase complex, soluble; plasma membrane; protein complex
Molecular Function: adenylate cyclase activity; cytidylate cyclase activity; GTP binding; guanylate cyclase activity; heme binding; ion binding; nucleotide binding; protein heterodimerization activity
Biological Process: cAMP biosynthetic process; cGMP biosynthetic process; nitric oxide mediated signal transduction; positive regulation of cGMP biosynthetic process; regulation of blood pressure; relaxation of vascular smooth muscle; response to defense-related host nitric oxide production; response to herbicide; response to organic cyclic substance
Research Articles on Gucy1a3
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Product Notes
The Gucy1a3 gucy1a3 (Catalog #AAA544848) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Guanylyl Cyclase alpha 1 Antibody BIOTIN reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Soluble Guanylyl Cyclase alpha 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). ELISA: 1:10,000 Immunoprecipitation: 1:200 Western Blot: 1:500. Researchers should empirically determine the suitability of the Gucy1a3 gucy1a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Soluble Guanylyl Cyclase alpha 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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