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ENT1 blocking peptide

ENT1 Peptide

Gene Names
Slc29a1; ENT1; AA407560; 1200014D21Rik
Applications
Immunodepletion, Immunocompetition
Synonyms
ENT1; ENT1 Peptide; Equilibrative NBMPR-sensitive nucleoside transporter; Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter; Equilibrative nucleoside transporter 1; es-type; Nucleoside transporter; Slc29a1; solute carrier family 29 (equilibrative nucleoside transporter); member 1; Solute carrier family 29 member 1 antibody; ENT1 blocking peptide
Ordering
For Research Use Only!
Form/Format
Antigenic Blocking Peptide
Concentration
0.5 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
460
Applicable Applications for ENT1 blocking peptide
Immunodepletion, Immunocompetition
Application Notes
ELISA: 1:10,000
Western Blot: 1:500
Immunogen
Synthetic peptide taken within amino acid reigon 410-460 on mouse Equilibrative nitrobenzylthioinosine-sensitive nucleoside transporter ENT1 protein.
Expression
Highly expressed in heart, spleen, lung, liver and testis. Lower level of expression in brain and kidney.
Molecular Function
Nucleoside transmembrane transporter activity
Structure
Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
Subcellular Location
Cell membrane; Basolateral cell membrane; Apical cell membrane
Preparation and Storage
-20 degree C for long term storage
Related Product Information for ENT1 blocking peptide
Antigenic Blocking Peptide Equilibrative nitrobenzylthioinosine-sensitive nucleoside transporter ENT1
Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Resistant to dipyridamole and dilazep inhibition (anticancer chemotherapeutics drugs).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
50,076 Da
NCBI Official Full Name
equilibrative nitrobenzylthioinosine-sensitive nucleoside transporter ENT1
NCBI Official Synonym Full Names
solute carrier family 29 (nucleoside transporters), member 1
NCBI Official Symbol
Slc29a1
NCBI Official Synonym Symbols
ENT1; AA407560; 1200014D21Rik
NCBI Protein Information
equilibrative nucleoside transporter 1
UniProt Protein Name
Equilibrative nucleoside transporter 1
Protein Family
UniProt Gene Name
Slc29a1
UniProt Synonym Gene Names
Ent1; Equilibrative NBMPR-sensitive nucleoside transporter
UniProt Entry Name
S29A1_MOUSE

Uniprot Description

SLC29A1: Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs). Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.

Protein type: Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass; Transporter

Cellular Component: apical plasma membrane; basolateral plasma membrane; integral to membrane; integral to plasma membrane; membrane; plasma membrane

Molecular Function: nucleoside transmembrane transporter activity

Biological Process: nucleoside transport; regulation of excitatory postsynaptic membrane potential; sleep; transport; uridine transport

Research Articles on ENT1

Similar Products

Product Notes

The ENT1 slc29a1 (Catalog #AAA543631) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ENT1 can be used in a range of immunoassay formats including, but not limited to, Immunodepletion, Immunocompetition. ELISA: 1:10,000 Western Blot: 1:500. Researchers should empirically determine the suitability of the ENT1 slc29a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ENT1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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