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Rabbit CaMKII gamma Polyclonal Antibody | anti-CAMK2G antibody

CAMKII gamma Antibody BIOTIN-Conjugated

Gene Names
CAMK2G; CAMK; CAMKG; CAMK-II
Reactivity
Human, Mouse, Rat
Applications
Dot Blot, ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Synonyms
CaMKII gamma; Polyclonal Antibody; CAMKII gamma Antibody BIOTIN-Conjugated; Calcium/calmodulin dependent protein kinase type 1G; CaM kinase I gamma; CaM kinase IG; CaMK-like CREB kinase III; Camk1g; CLICK III; VWS1 antibody; anti-CAMK2G antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Form/Format
BIOTIN-Conjugated
Concentration
0.8 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
558
Applicable Applications for anti-CAMK2G antibody
Confocal Microscopy (CM), Dot Blot (DB), ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
Confocal Microscopy||1:200
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunocytochemistry: 1:200
Immunofluorescence: 1:200
Immunohistochemistry: 1:200
Immunoprecipitation: 1:200
Western Blot: 1:500
Immunogen
Recombinant GST-fusion protein of Calcium/Calmodulin-Dependent kinase 11 gamma
Expression
Skeletal muscle
Determinant
N-epitope
Molecular Function
Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase
Structure
CAMK2 is composed of 4 different chains: alpha (CAMK2A), beta (CAMK2B), gamma (CAMK2G), and delta (CAMK2D). The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 12 subunits with two hexameric rings stacked one on top of the other.
Subcellular Location
Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side
Preparation and Storage
-20 degree C for long term storage
Related Product Information for anti-CAMK2G antibody
BIOTIN-Conjugated Calcium/calmodulin-dependent protein kinase type II subunit gamma isoform 3 Antibody N-epitope
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
818
Molecular Weight
55,961 Da
NCBI Official Full Name
Calcium/calmodulin-dependent protein kinase type II subunit gamma
NCBI Official Synonym Full Names
calcium/calmodulin dependent protein kinase II gamma
NCBI Official Symbol
CAMK2G
NCBI Official Synonym Symbols
CAMK; CAMKG; CAMK-II
NCBI Protein Information
calcium/calmodulin-dependent protein kinase type II subunit gamma
UniProt Protein Name
Calcium/calmodulin-dependent protein kinase type II subunit gamma
UniProt Gene Name
CAMK2G
UniProt Synonym Gene Names
CAMK; CAMK-II; CAMKG; CaM kinase II subunit gamma; CaMK-II subunit gamma
UniProt Entry Name
KCC2G_HUMAN

NCBI Description

The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.[provided by RefSeq, Mar 2011]

Uniprot Description

Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.

Research Articles on CAMK2G

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Product Notes

The CAMK2G camk2g (Catalog #AAA541135) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CAMKII gamma Antibody BIOTIN-Conjugated reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CaMKII gamma can be used in a range of immunoassay formats including, but not limited to, Confocal Microscopy (CM), Dot Blot (DB), ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). Confocal Microscopy||1:200 Dot Blot: 1:10,000 ELISA: 1:10,000 Immunocytochemistry: 1:200 Immunofluorescence: 1:200 Immunohistochemistry: 1:200 Immunoprecipitation: 1:200 Western Blot: 1:500. Researchers should empirically determine the suitability of the CAMK2G camk2g for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CaMKII gamma, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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