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Rabbit GPCR LGR6 Polyclonal Antibody | anti-GPCR LGR6 antibody

GPCR LGR6 Antibody Affinity Purified

Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Synonyms
GPCR LGR6; Polyclonal Antibody; GPCR LGR6 Antibody Affinity Purified; FLJ14471; Gonadotropin receptor; GPCR; Leucine-rich repeat-containing G protein-coupled receptor 6; Lgr6; VTS20631 antibody; anti-GPCR LGR6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Form/Format
Affinity Purified
Concentration
0.58-0.65 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
915
Applicable Applications for anti-GPCR LGR6 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Dot Blot: 1:10,000
ELISA: 1:10,000
Western Blot: 1:500
Immunogen
Synthetic peptide taken within amino acid region 850-920 on human LRG6 protein.
Molecular Function
Transmembrane signaling receptor activity
Subcellular Location
Cell membrane, multi-pass membrane protein
Preparation and Storage
-20 degree C for long term storage
Related Product Information for anti-GPCR LGR6 antibody
Affinity Purified Leucine-rich repeat-containing G protein-coupled receptor 6 Antibody
Receptor for R-spondins that potentiates canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in epidermis.
Product Categories/Family for anti-GPCR LGR6 antibody

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
99,295 Da
UniProt Protein Name
Leucine-rich repeat-containing G-protein coupled receptor 6
UniProt Gene Name
LGR6
UniProt Entry Name
LGR6_HUMAN

Uniprot Description

LGR6: a leucine-rich repeat-containing G-protein-coupled receptor. Receptor for R-spondins, potent stimulators of adult stem cell proliferation. A marker of adult stem cells. A Wnt receptor component that enhances Wnt signaling by soluble R-spondin proteins. A marker of a multipotent population of skin stem cells. Three isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; Tumor suppressor; GPCR, family 1

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: integral to plasma membrane; plasma membrane; trans-Golgi network membrane; vesicle

Molecular Function: G-protein coupled receptor activity; protein binding; transmembrane receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of cell migration; positive regulation of Wnt receptor signaling pathway; Wnt receptor signaling pathway

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Product Notes

The GPCR LGR6 lgr6 (Catalog #AAA540200) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GPCR LGR6 Antibody Affinity Purified reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GPCR LGR6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Dot Blot: 1:10,000 ELISA: 1:10,000 Western Blot: 1:500. Researchers should empirically determine the suitability of the GPCR LGR6 lgr6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPCR LGR6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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