ApoE3 recombinant protein
ApoE3 protein
Applications
User optimized
Purity
>=90% by SDS-PAGE gel and HPLC
Synonyms
ApoE3; ApoE3 protein; Apoprotein E3 protein; Apo-E3 protein; Apo E3 protein; ApoE 3; ApoE-3 protein; ApoE-3; ApoE 3 protein; ApoE3 recombinant protein
Host
E.coli
Purity/Purification
>=90% by SDS-PAGE gel and HPLC
Sequence
Region of ApoE3 protein corresponding to amino acids MKVEQAVETE PEPELRQQTE WQSGQRWELA LGRFWDYLRW VQTLSEQVQE ELLSSQVTQE LRALMDETMK ELKAYKSELE EQLTPVAEET RARLSKELQA AQARLGADME DVCGRLVQYR GEVQAMLGQS TEELRVRLAS HLRKLRKRLL RDADDLQKRL AVYQAGAREG AERGLSAIRE RLGPLVEQGR VRAATVGSLA GQPLQERAQA WGERLRARME EMGSRTRDRL DEVKEQVAEV RAKLEEQAQQ IRLQAEAFQA RLKSWFEPLV EDMQRQWAGL VEKVQAAVGT SAAPVPSDNH.
Applicable Applications for ApoE3 recombinant protein
User optimized
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Grade
Recombinant human protein
Species
Human
Form
Lyophilized from 20mM Sodium Phosphate, pH 7.8, with 0.5 mM DTT. Sterile filtered through a 0.2 micron filter. Centrifuge vial prior to opening. Reconstitute in 20 mM Sodium Phosphate, pH 7.8, and 0.5 mM DTT to a concentration of 1.0 mg/ml. DO NOT VORTEX. This solution can be stored at 4 degree C for one week.
Biohazard
Not for human use. Use normal laboratory precautions when handling.
Biological Significance
ApoE3 belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in liver and brain and to some extent in almost every organ. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. E3 is the most common isoform and is present in 40-90% of the population.
Preparation and Storage
Ships on blue ice. Upon receipt store at 4 degree C short term, -20 degree C long term. After reconstitution this product is table for 1 week at 4 degree C. Working aliquots stored with a carrier protein are stable for at least 3 months at -20 degree C. Avoid repeated freeze/thaw cycles.
Related Product Information for ApoE3 recombinant protein
Purified recombinant Human ApoE3 protein
Product Categories/Family for ApoE3 recombinant protein
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Product Notes
The ApoE3 (Catalog #AAA538089) is a Recombinant Protein produced from E.coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ApoE3 can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the ApoE3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Region of ApoE3 protein correspond ing to amino acids MKVEQAVETE PEPELRQQTE WQSGQRWELA LGRFWDYLRW VQTLSEQVQE ELLSSQVTQE LRALMDETMK ELKAYKSELE EQLTPVAEET RARLSKELQA AQARLGADME DVCGRLVQYR GEVQAMLGQS TEELRVRLAS HLRKLRKRLL RDADDLQKRL AVYQAGAREG AERGLSAIRE RLGPLVEQGR VRAATVGSLA GQPLQERAQA WGERLRARME EMGSRTRDRL DEVKEQVAEV RAKLEEQAQQ IRLQAEAFQA RLKSWFEPLV EDMQRQWAGL VEKVQAAVGT SAAPVPSDNH. It is sometimes possible for the material contained within the vial of "ApoE3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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