Western Blot (WB)
(Western blot analysis of ApoE4 using recombinant human ApoE4. Lane 1: 250ng. Lane 2: 1 ug.)
Rabbit ApoE4 Polyclonal Antibody | anti-ApoE4 antibody
ApoE4 antibody
Applications
Western Blot
Purity
ApoE4 antibody was purified by affinity chromatography
Synonyms
ApoE4; Polyclonal Antibody; ApoE4 antibody; Polyclonal ApoE4; anti-ApoE4; ApoE-4; APOE4; APOE-4; ApoE 4; APOE 4; Apolipoprotein E4; anti-ApoE4 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
ApoE4 antibody was purified by affinity chromatography
Form/Format
Supplied in PBS buffer, pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Concentration
500 ug/ml (varies by lot)
Applicable Applications for anti-ApoE4 antibody
Western Blot (WB)
Application Notes
WB: 0.5-4 ug/ml
Biological Significance
ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in liver and brain and to some extent in almost every organ. ApoE is an important constituent of all plasma lipoproteins. It?s interaction with specific ApoE receptor enables uptake of chylomicron remnants by liver cells, which is an essential step during normal lipid metabolism. It also binds with the LDL receptor. Defects in ApoE are a cause of hyperlipoproteinemia type III. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Individuals heterozygous for the ApoE4 allele are at higher risk of late-onset Alzheimer?s disease.
Cross-Reactivity
Human
Immunogen
ApoE4 antibody was raised in Rabbit using recombinant human ApoE4 as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of ApoE4 using recombinant human ApoE4. Lane 1: 250ng. Lane 2: 1 ug.)
Western Blot (WB)
(Western blot analysis of ApoE4 using recombinant human ApoE4. Lane 1: 250ng. Lane 2: 1 ug.)
Related Product Information for anti-ApoE4 antibody
Rabbit polyclonal ApoE4 antibody
Product Categories/Family for anti-ApoE4 antibody
Similar Products
Product Notes
The ApoE4 (Catalog #AAA837412) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ApoE4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 0.5-4 ug/ml. Researchers should empirically determine the suitability of the ApoE4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ApoE4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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