IFN alpha 2 active protein

IFN alpha 2 protein (Monkey)

Cat. Num. AAA537874

• Gene Names: IFNA2; IFNA; INFA2; IFNA2B; IFN-alphaA
• Applications: User optimized
• Purity: > 98% pure
• Synonyms: IFN alpha 2; IFN alpha 2 protein (Monkey); Interferon alpha 2 protein; Cynomologous IFN alpha 2 protein; Rhesus IFN alpha 2 protein; IFN alpha 2 active protein

• Host: Monkey
• Purity/Purification: > 98% pure
• Form/Format: Stored in PBS buffer with 0.1% BSA. Dilute only in bufflers containing protein such as 0.1% BSA.
• Concentration: Activity: 4.77 x 10⁶units/ml; Specific Activity: 1.98 x 10⁸ units/mg (varies by lot)
• Sequence Length: 72

• Applicable Applications for IFN alpha 2 active protein: User optimized
• Protein Type: Recombinant
• Biological Significance: Interferons (IFNs) are proteins made and released by lymphocytes in response to the presence of pathogens-such as viruses, bacteria, or parasites-or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors.
• Bioactivity: The EC50 for interferon in a cytopathic effect inhibition assay is ~1 U/ml (Human), ~5 U/ml (Bovine) and ~200 U/ml (Rhesus)
• Endotoxin Levels: <1 EU/ug
• Grade: Highly pure
• Expression System: Rhesus cDNA expressed in E.Coli
• Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
• Biohazard: Use standard laboratory precautions when handling this material.
• Preparation and Storage: Upon receipt store at -20 degree C short-term, -70 degree C long term. Keep freeze thaw to a minimum; Shipping: Ships with Dry Ice.

Related Product Information for IFN alpha 2 active protein

Purified recombinant Monkey IFN alpha 2 protein

Product Categories/Family for IFN alpha 2 active protein

Immunology

NCBI and Uniprot Product Information

• NCBI GI #: 4261660
• NCBI GeneID: 3440
• UniProt Accession #: Q16054; P01563
• Molecular Weight: 19.5 kDa
• NCBI Official Full Name: interferon alpha 2, partial
• NCBI Official Synonym Full Names: interferon, alpha 2
• NCBI Official Symbol: IFNA2
• NCBI Official Synonym Symbols: IFNA; INFA2; IFNA2B; IFN-alphaA
• NCBI Protein Information: interferon alpha-2
• UniProt Protein Name: IFN-<alpha>2 protein
• UniProt Gene Name: IFN-<alpha>2
• UniProt Entry Name: Q16054_HUMAN

NCBI Description

This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold. [provided by RefSeq, Jun 2011]

Uniprot Description

IFNA2: Produced by macrophages, IFN-alpha have antiviral activities. Belongs to the alpha/beta interferon family.

Protein type: Secreted, signal peptide; Secreted; Membrane protein, integral

Chromosomal Location of Human Ortholog: 9p22

Cellular Component: extracellular space; extracellular region

Molecular Function: protein binding; interferon-alpha/beta receptor binding; cytokine activity

Biological Process: cell surface receptor linked signal transduction; cell-cell signaling; negative regulation of virion penetration into host cell; apoptosis; cytokine and chemokine mediated signaling pathway; innate immune response; negative regulation of transcription, DNA-dependent; blood coagulation; inflammatory response; defense response to virus; negative regulation of T cell differentiation; positive regulation of tyrosine phosphorylation of Stat3 protein