Prothrombin Native Protein | F2 native protein
Prothrombin protein (Bovine)
Reactivity
Bovine
Applications
User optimized
Purity
> 95% pure
Synonyms
Prothrombin; Prothrombin protein (Bovine); Bovine Prothrombin Protein; F2 native protein
Host
Bovine
Reactivity
Bovine
Purity/Purification
> 95% pure
Form/Format
Supplied as a liquid in 50% (vol/vol) glycerol/deionized water.
Concentration
7.5 mg/ml (varies by lot)
Sequence Length
625
Applicable Applications for F2 native protein
User optimized
Source
Prepare from bovine fresh plasma
Protein Type
Native
Biological Significance
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to gamma-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes.
Contaminants
Molecular Weight: 72,000 daltons E1%, 1cm, 280nm = 14.4
Biohazard Information
Use appropriate laboratory precautions while hanlding this product. For in VITRO research use only
Preparation and Storage
Upon receipt store at -20 degree C. Avoid repeated Freeze/Thaw cycles.
Product Categories/Family for F2 native protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
72 kDa
NCBI Official Full Name
prothrombin
NCBI Official Symbol
F2
NCBI Protein Information
prothrombin
UniProt Protein Name
Prothrombin
Protein Family
UniProt Gene Name
F2
UniProt Entry Name
THRB_BOVIN
Uniprot Description
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing ().
Research Articles on F2
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Product Notes
The F2 f2 (Catalog #AAA537279) is a Native Protein produced from Bovine and is intended for research purposes only. The product is available for immediate purchase. The Prothrombin protein (Bovine) reacts with Bovine and may cross-react with other species as described in the data sheet. AAA Biotech's Prothrombin can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the F2 f2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Prothrombin, Native Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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