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Rabbit anti-Human PIGF PIGF Polyclonal Antibody | anti-PIGF antibody

PIGF antibody

Reactivity
Human PIGF
Applications
ELISA, Western Blot
Synonyms
PIGF; Polyclonal Antibody; PIGF antibody; Polyclonal PIGF; Anti-PIGF; Placenta Growth Factor-1; PIGF-1; PGF; anti-PIGF antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human PIGF
Clonality
Polyclonal
Specificity
Human PIGF
Form/Format
Lyophilized from PBS, pH 7.2.
Sequence Length
219
Applicable Applications for anti-PIGF antibody
ELISA (EIA), Inhibition, Western Blot (WB)
Biological Significance
PlGF-1 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-1 is expressed in placental tissues, colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration.
Immunogen
PIGF antibody was raised in rabbit using highly pure recombinant human PlGF as the immunogen.
Preparation and Storage
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-PIGF antibody
Affinity purified Rabbit polyclonal PIGF antibody
Product Categories/Family for anti-PIGF antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
29.7 kDa (predicted detection band MW)
NCBI Official Full Name
phosphatidylinositol-glycan biosynthesis class F protein isoform 1
NCBI Official Synonym Full Names
phosphatidylinositol glycan anchor biosynthesis, class F
NCBI Official Symbol
PIGF
NCBI Protein Information
phosphatidylinositol-glycan biosynthesis class F protein
UniProt Protein Name
Phosphatidylinositol-glycan biosynthesis class F protein
UniProt Gene Name
PIGF
UniProt Synonym Gene Names
PIG-F
UniProt Entry Name
PIGF_HUMAN

NCBI Description

This gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

PIGF: Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI. Belongs to the PIGF family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2p21-p16

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: ethanolaminephosphotransferase activity

Biological Process: cellular protein metabolic process; preassembly of GPI anchor in ER membrane; GPI anchor biosynthetic process; C-terminal protein lipidation; post-translational protein modification

Research Articles on PIGF

Similar Products

Product Notes

The PIGF pigf (Catalog #AAA535816) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PIGF antibody reacts with Human PIGF and may cross-react with other species as described in the data sheet. AAA Biotech's PIGF can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Inhibition, Western Blot (WB). Researchers should empirically determine the suitability of the PIGF pigf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIGF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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