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Rabbit anti-Murine MCP5 MCP5 Polyclonal Antibody | anti-MCP5 antibody

MCP5 antibody

Gene Names
mcp5; mug21; num1
Reactivity
Murine MCP5
Applications
ELISA, Western Blot
Synonyms
MCP5; Polyclonal Antibody; MCP5 antibody; Polyclonal MCP5; Anti-MCP5; CCL12; MCP-5; MCP 5; Monocyte Chemotactic-5; anti-MCP5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Murine MCP5
Clonality
Polyclonal
Specificity
Murine MCP5
Form/Format
Lyophilized from PBS, pH 7.2.
Sequence Length
968
Applicable Applications for anti-MCP5 antibody
ELISA (EIA), Inhibition, Western Blot (WB)
Application Notes
ELISA: 0.5-2 ug/ml
Inhibition: 2-3 ug/ml
WB: 0.1-0.2 ug/ml
Biological Significance
Chemokine (C-C motif) ligand 12 (CCL12) is a small cytokine belonging to the CC chemokine family that has been described in mice. It is also known as monocyte chemotactic protein 5 (MCP-5) and, due to its similarity with the human chemokine MCP-1, sometimes it is called MCP-1-related chemokine. CCL12 specifically attracts eosinophils, monocytes and lymphocytes. This chemokine is found predominately in lymph nodes and thymus under normal conditions, and its expression can be hugely induced in macrophages.
Immunogen
MCP5 antibody was raised in rabbit using highly pure recombinant murine MCP-5 as the immunogen.
Preparation and Storage
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-MCP5 antibody
Affinity purified Rabbit polyclonal MCP5 antibody
Product Categories/Family for anti-MCP5 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
9.3 kDa (predicted detection band MW)
NCBI Official Full Name
Meiotic coiled-coil protein 5
NCBI Official Symbol
mcp5
NCBI Official Synonym Symbols
mug21; num1
NCBI Protein Information
cortical anchoring factor for dynein Mcp5/Num1
UniProt Protein Name
Meiotic coiled-coil protein 5
UniProt Gene Name
mcp5
UniProt Synonym Gene Names
mug21; num1
UniProt Entry Name
MCP5_SCHPO

Uniprot Description

Involved in chromosome segregation. Facilitates nuclear oscillation during meiotic prophase I, the 'horsetail' phase, by acting as a dynein anchor. Essential for anchoring dhc1 to the cortex. Required for proper sliding of the microtubules along the cell cortex, which leads to the proper U-turn movement of the nucleus.

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Product Notes

The MCP5 mcp5 (Catalog #AAA535803) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MCP5 antibody reacts with Murine MCP5 and may cross-react with other species as described in the data sheet. AAA Biotech's MCP5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Inhibition, Western Blot (WB). ELISA: 0.5-2 ug/ml Inhibition: 2-3 ug/ml WB: 0.1-0.2 ug/ml. Researchers should empirically determine the suitability of the MCP5 mcp5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCP5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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