Western Blot (WB)
(Western blot analysis of Histone Deacetylase 3 expression in HeLa (A); C32 (B); NIH3T3 (C); Raw264.7 (D); PC12 (E); rat heart (F) whole cell lysates.)
Rabbit Histone Deacetylase 3 Polyclonal Antibody | anti-HD3 antibody
Histone Deacetylase 3 Antibody
Gene Names
HDAC3; HD3; RPD3; KDAC3; RPD3-2
Applications
Western Blot, Immunohistochemistry, Immunofluorescence, Immunocytochemistry
Purity
Immunogen Affinity Chromatography
Synonyms
Histone Deacetylase 3; Polyclonal Antibody; Histone Deacetylase 3 Antibody; Purified Polyclonal Histone Deacetylase 3 Antibody; Polyclonal Histone Deacetylase 3 antibody; Anti-Histone Deacetylase 3 antibody; Histone deacetylase 3 antibody; HD3 antibody; RPD3-2 antibody; SMAP45 antibody; anti-HD3 antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of Histone Deacetylase 3 protein
Purity/Purification
Immunogen Affinity Chromatography
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Sequence Length
428
Applicable Applications for anti-HD3 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes
WB: 1:500-1:1000
IHC: 1:100-1:200
IF: 1:100-1:500
ICC: 1:100-1:500
IHC: 1:100-1:200
IF: 1:100-1:500
ICC: 1:100-1:500
Immunogen
Histone Deacetylase 3 antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Histone Deacetylase 3 as the immunogen
Cross-Reactivity
Mouse, Rat, Bovine, Chicken, Dog, Pig
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of Histone Deacetylase 3 expression in HeLa (A); C32 (B); NIH3T3 (C); Raw264.7 (D); PC12 (E); rat heart (F) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of Histone Deacetylase 3 expression in HeLa (A); C32 (B); NIH3T3 (C); Raw264.7 (D); PC12 (E); rat heart (F) whole cell lysates.)
Related Product Information for anti-HD3 antibody
Histone Deacetylase 3 is a responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Product Categories/Family for anti-HD3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
histone deacetylase 3
NCBI Official Synonym Full Names
histone deacetylase 3
NCBI Official Symbol
HDAC3
NCBI Official Synonym Symbols
HD3; RPD3; KDAC3; RPD3-2
NCBI Protein Information
histone deacetylase 3
Protein Family
NCBI Description
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]
Research Articles on HD3
Similar Products
Product Notes
The HD3 (Catalog #AAA5315268) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Histone Deacetylase 3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC). WB: 1:500-1:1000 IHC: 1:100-1:200 IF: 1:100-1:500 ICC: 1:100-1:500. Researchers should empirically determine the suitability of the HD3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Histone Deacetylase 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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