Western Blot (WB)
(Western blot analysis of APC expression in HeLa (A); HEK293T (B); SW480 (C); rat testis (D) whole cell lysates.)
Rabbit APC Polyclonal Antibody | anti-APC antibody
APC Antibody
Gene Names
APC; GS; DP2; DP3; BTPS2; DP2.5; PPP1R46
Applications
Western Blot, Immunohistochemistry, Immunofluorescence, Immunocytochemistry
Purity
Immunogen Affinity Chromatography
Synonyms
APC; Polyclonal Antibody; APC Antibody; Purified Polyclonal APC Antibody; Polyclonal APC antibody; Anti-APC antibody; DP2.5 antibody; Adenomatous polyposis coli protein antibody; Protein APC antibody; Deleted in polyposis 2.5 antibody; anti-APC antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of APC protein
Purity/Purification
Immunogen Affinity Chromatography
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Sequence Length
2843
Applicable Applications for anti-APC antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes
WB: 1:500-1:1000
IHC: 1:100-1:200
IF: 1:100-1:500
ICC: 1:100-1:500
IHC: 1:100-1:200
IF: 1:100-1:500
ICC: 1:100-1:500
Immunogen
APC antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human APC as the immunogen
Cross-Reactivity
Rat, Bovine, Cat, Pig
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of APC expression in HeLa (A); HEK293T (B); SW480 (C); rat testis (D) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of APC expression in HeLa (A); HEK293T (B); SW480 (C); rat testis (D) whole cell lysates.)
Related Product Information for anti-APC antibody
APC is a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway.
Product Categories/Family for anti-APC antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
APC
NCBI Official Synonym Full Names
APC regulator of WNT signaling pathway
NCBI Official Symbol
APC
NCBI Official Synonym Symbols
GS; DP2; DP3; BTPS2; DP2.5; PPP1R46
NCBI Protein Information
adenomatous polyposis coli protein
Protein Family
NCBI Description
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]
Research Articles on APC
Similar Products
Product Notes
The APC (Catalog #AAA5313996) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's APC can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC). WB: 1:500-1:1000 IHC: 1:100-1:200 IF: 1:100-1:500 ICC: 1:100-1:500. Researchers should empirically determine the suitability of the APC for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "APC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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