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Mouse Rheumatoid Factor Monoclonal Antibody

Rheumatoid Factor antibody

Reactivity
Reacts with 30% of IgM-RF paraproteins from unrelated individuals. It does not recognize IgM, IgA, or IgG proteins lacking RF, nor with pooled F (ab')2 fragments.
Applications
ELISA
Synonyms
Rheumatoid Factor; Monoclonal Antibody; Rheumatoid Factor antibody; Monoclonal Rheumatoid Factor; Anti-Rheumatoid Factor; RF; Anti Rheumatoid Factor; anti-Rheumatoid Factor antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Reacts with 30% of IgM-RF paraproteins from unrelated individuals. It does not recognize IgM, IgA, or IgG proteins lacking RF, nor with pooled F (ab')2 fragments.
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
M310120
Specificity
Human rheumatoid factor
Form/Format
Protein G purified Ig, supplied in PBS buffer, pH 7.4 with NO PRESERVATIVES ADDED.
Concentration
0.8mg/ml (varies by lot)
Sequence Length
107
Applicable Applications for anti-Rheumatoid Factor antibody
ELISA (EIA)
Application Notes
ELISA: 1:1,600
Immunogen
Purified proteins from patients with IgM cryoglobulins
Biological Significance
Rheumatoid factor (RF or RhF) is an autoantibody (antibody directed against an organism's own tissues) most relevant in rheumatoid arthritis.[1] It is an antibody against the Fc portion of IgG, which is itself an antibody. RF and IgG join to form immune complexes that contribute to the disease process.
Preparation and Storage
4°C short term only, for routine storage, aliquot and freeze at -20°C to 70°C.
Related Product Information for anti-Rheumatoid Factor antibody
Mouse monoclonal Rheumatoid Factor antibody
Product Categories/Family for anti-Rheumatoid Factor antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI Official Full Name
rheumatoid factor, partial

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Product Notes

The Rheumatoid Factor (Catalog #AAA531193) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Rheumatoid Factor antibody reacts with Reacts with 30% of IgM-RF paraproteins from unrelated individuals. It does not recognize IgM, IgA, or IgG proteins lacking RF, nor with pooled F (ab')2 fragments. and may cross-react with other species as described in the data sheet. AAA Biotech's Rheumatoid Factor can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1:1,600. Researchers should empirically determine the suitability of the Rheumatoid Factor for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Rheumatoid Factor, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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