Testing Data
Rat anti-Mouse CD5 Monoclonal Antibody | anti-CD5 antibody
Anti-Mouse CD5, Biotin (Clone 53-7.3) (rat IgG2a)
Reactivity
Mouse
Synonyms
CD5; Monoclonal Antibody; Anti-Mouse CD5; Biotin (Clone 53-7.3) (rat IgG2a); Purified Anti Mouse CD5 (Ly-1) Monoclonal Antibody; anti-CD5 antibody
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
Rat IgG2a
Clone Number
53-7.3
Specificity
CD5 (Mouse/Human CD5 transmembrane glycoprotein)
Form/Format
Biotin
Concentration
0.1 mg/ml (varies by lot)
Sequence Length
463
Immunogen
Mouse thymus or spleen
Donor
Balb/c mouse thymus or spleen
Presentation
Biotin/FITC/PE conjugated IgG buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
Preparation and Storage
For all formats, store at 4 degree C. DO NOT FREEZE PE conjugates. For long term storage (Ascites, Purified, Biotin, FITC and NA), aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
Testing Data
Testing Data
Related Product Information for anti-CD5 antibody
anti-mouse CD5 (Ly-1) Monoclonal Antibody is specific for the mouse CD5 antigen. This transmembrane glycoprotein is a T-cell associated marker that is also expressed by two B-cell neoplasms, lymphocytic leukemia and mantle cell lymphoma. CD5 is expressed on all T cells early in development, a subset of B cells described as B1aB cells, 95% of thymocytes and 72% of peripheral blood lymphocytes. CD5 has a molecular weight of 67KDa and belongs to the cysteine-rich macrophage scavenger receptor family of proteins.The CD5 receptor is physically associated with the antigen receptor complex in both T and B cells and modulates intracellular signals initiated by both TCR and BCR. CD5 is also a counter receptor for CD72. This clone (53-7.3) has been reported to work in Immunohistochemistry on acetone fixed frozen sections and zinc fixed paraffin sections, Immunoprecipitation and Flow Cytometry.
NCBI and Uniprot Product Information
Uniprot Description
CD5: a surface glycoprotein expressed on T cells and B-1 B cells. Rapidly recruited to the immunological synapse, lowering the response of the T cell antigen receptor. CD5 interacts with CD72/LYB-2. Promotes B-cell survival through stimulation of autocrine IL-10 production. Contains 3 SRCR domains.
Protein type: Cell surface; Membrane protein, integral
Chromosomal Location of Human Ortholog: 11q13
Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane
Molecular Function: protein binding; transmembrane receptor activity; receptor activity; scavenger receptor activity
Biological Process: receptor-mediated endocytosis; cell proliferation; T cell costimulation; cell recognition
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Product Notes
The CD5 (Catalog #AAA520632) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse CD5, Biotin (Clone 53-7.3) (rat IgG2a) reacts with Mouse and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "CD5, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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