Testing Data
Cantharidin, Inhibitor
Cantharidin
Purity
>98% (HPLC)
Synonyms
Cantharidin; 3alpha; 7alpha-Dimethylhexahydro-4; 7-epoxyisobenzofuran-1; 3-dione; inhibitor
Purity/Purification
>98% (HPLC)
Specific Activity
Phosphatase PP2A Inhibitor
CAS Registry Number
56-25-7
Molecular Formula
C10H12O4
Solubility
May be dissolved in DMSO (20mg/ml); or ethanol (5mg/ml)
Preparation and Storage
Store as supplied at -20 degree C for up to 2 years. Store solutions at -20 degree C for up to 2 weeks.
Testing Data
Testing Data
Related Product Information for Cantharidin, inhibitor
Inhibits protein phosphatase 2A (Ki=0.19 uM) and PP1 (Ki=1.1 uM)1. Displays >500-fold selectivity over PP2B. Suppresses growth and migration of PANC-1 pancreatic cancer cells via phosphorylation and degradation of beta-catenin2. Arrests G2/M transition via JNK/Sp1-dependent down-regulation of CDK13. Cell permeable.
Product Categories/Family for Cantharidin, inhibitor
References
1. RE Honkanen FEBS Lett. 1993 330:283
2. MY Wu et al. Oncol. Rep. 2014 32:513
3. FR Gong et al. Oncotarget 2015 6:18469
2. MY Wu et al. Oncol. Rep. 2014 32:513
3. FR Gong et al. Oncotarget 2015 6:18469
Similar Products
Product Notes
The Cantharidin (Catalog #AAA516403) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Cantharidin, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
