Western Blot (WB)
(Sample Data: Western blot analysis of BID in mouse lung cell lysates with BID antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.)
Rabbit anti-Human, Mouse BID Polyclonal Antibody | anti-BID antibody
Anti-BID
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
Affinity chromatography
Synonyms
BID; Polyclonal Antibody; Anti-BID; anti-BID antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit, IgG
Specificity
Recognizes the BID protein
Purity/Purification
Affinity chromatography
Form/Format
PBS + 0.02% sodium azide
Applicable Applications for anti-BID antibody
Western Blot (WB), ELISA
Immunogen
BID antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human BID
Preparation and Storage
Store at 4 degree C (add 0.1% NaN3) for several months, and at -20 degree C for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
1 year at -20 degree C from date of shipment
1 year at -20 degree C from date of shipment
Western Blot (WB)
(Sample Data: Western blot analysis of BID in mouse lung cell lysates with BID antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.)
Western Blot (WB)
(Sample Data: Western blot analysis of BID in mouse lung cell lysates with BID antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.)
Related Product Information for anti-BID antibody
BID is a BH3 interacting death domain that heterodimerizes with either agonist BAX or antagonist BCL2 (1). BID is a member of the BCL-2 family of cell death regulators and is a mediator of mitochondrial damage induced by caspase-8 (CASP8). BID initiates apoptosis by binding to regulatory sites on prosurvival BCL2 proteins to directly neutralize their function. Multiple alternatively spliced transcript variants of BID have been found, but the full-length nature of some variants has not been defined. BID together with Cathepsins play an important role in the actions of Camptothecin on breast cancer cells (2).
Product Categories/Family for anti-BID antibody
References
1. Hayakawa, A. et al:, Bid truncation mediated by caspases-3 and -9 in vinorelbine-induced apoptosis. Apoptosis. 2008;13(4):523-30.
2. Lamparska-Przybysz. M. et al: Cathepsins and BID are involved in the molecular switch between apoptosis and autophagy in breast cancer MCF-7 cells exposed to camptothecin. J PhysiolPharmacol. 2005 Jun;56Suppl 3:159-79.
2. Lamparska-Przybysz. M. et al: Cathepsins and BID are involved in the molecular switch between apoptosis and autophagy in breast cancer MCF-7 cells exposed to camptothecin. J PhysiolPharmacol. 2005 Jun;56Suppl 3:159-79.
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Product Notes
The BID (Catalog #AAA515879) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-BID reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's BID can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA. Researchers should empirically determine the suitability of the BID for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BID, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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