Assay Data
(Binding of Anti-2019-nCoV N-protein, HRP-conjugated (C19NP-60DH) to immobilized 2019-nCoV RBD-N Protein Chimera (C19NSD-G241H) determined by ELISA)
Human COVID 19 Nucleocapsid (NP) hIgG Coronavirus Monoclonal Antibody | anti-COVID-19 antibody
Anti 2019-nCoV N-Protein hIgG Antibody, HRP conjugated
Synonyms
COVID 19 Nucleocapsid (NP) hIgG Coronavirus; Monoclonal Antibody; Anti 2019-nCoV N-Protein hIgG Antibody; HRP conjugated; 2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Nucleocapsid; Nucleoprotein (NP); anti-COVID-19 antibody
Host
Human
Clonality
Monoclonal
Isotype
Human, IgG
Specificity
Recognizes the 2019-nCoV N-Protein
Form/Format
1x PBS + 0.02% sodium azide
Antibody Type
Recombinant Antibody
Cross Reactivity
SARS-CoV N-Protein
Preparation and Storage
1 year at -20 degree C from date of shipment
Store product at -20 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. Product shipped on ice packs.
Store product at -20 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. Product shipped on ice packs.
Assay Data
(Binding of Anti-2019-nCoV N-protein, HRP-conjugated (C19NP-60DH) to immobilized 2019-nCoV RBD-N Protein Chimera (C19NSD-G241H) determined by ELISA)
Assay Data
(Binding of Anti-2019-nCoV N-protein, HRP-conjugated (C19NP-60DH) to immobilized 2019-nCoV RBD-N Protein Chimera (C19NSD-G241H) determined by ELISA)
Related Product Information for anti-COVID-19 antibody
Recombinant Human Monoclonal IgG Antibody
Overview: nCoV N-Protein / Nucleocapsid protein is an RNA-binding protein primarily involved in binding to the viral RNA genome during packaging of viral RNA into a helical ribonucleoprotein or nucleocapsid structure (1). In addition, N-protein regulates viral RNA synthesis during replication/transcription and modulates host-pathogen interactions, such as actin reorganization, host cell cycle progression, and apoptosis (2). N-Protein is abundantly expressed during infection and antibodies against N-Protein have been detected in confirmed cases of Covid-19. Therefore, N-Protein is a potent antigen that provides basis for future vaccine and test kit development (3).
Overview: nCoV N-Protein / Nucleocapsid protein is an RNA-binding protein primarily involved in binding to the viral RNA genome during packaging of viral RNA into a helical ribonucleoprotein or nucleocapsid structure (1). In addition, N-protein regulates viral RNA synthesis during replication/transcription and modulates host-pathogen interactions, such as actin reorganization, host cell cycle progression, and apoptosis (2). N-Protein is abundantly expressed during infection and antibodies against N-Protein have been detected in confirmed cases of Covid-19. Therefore, N-Protein is a potent antigen that provides basis for future vaccine and test kit development (3).
Product Categories/Family for anti-COVID-19 antibody
References
1. McBride R, et al: The Corona virus nucleocapsid is a multifunctional protein. Viruses. 2014, 6:2991-3018.
2. Surjit M, et al: The nucleocapsid protein of severe acute respiratory syndrome-Corona virus inhibits the activity of cyclin-cyclin-dependent kinase complex and blocks S phase progression in mammalian cells. J Biol Chem. 2006, 281:10669-10681.
3. Zeng W, et al: Biochemical characterization of SARS-CoV-2 nucleocapsid protein. Biochem Biophys Res Commun. 2020, 527(3):618?623.
2. Surjit M, et al: The nucleocapsid protein of severe acute respiratory syndrome-Corona virus inhibits the activity of cyclin-cyclin-dependent kinase complex and blocks S phase progression in mammalian cells. J Biol Chem. 2006, 281:10669-10681.
3. Zeng W, et al: Biochemical characterization of SARS-CoV-2 nucleocapsid protein. Biochem Biophys Res Commun. 2020, 527(3):618?623.
NCBI and Uniprot Product Information
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Product Notes
The COVID-19 (Catalog #AAA515759) is an Antibody produced from Human and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "COVID 19 Nucleocapsid (NP) hIgG Coronavirus, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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