Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane: Mouse stomach tissue lysate, Primary antibody: 863004(GKN2 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes)

Rabbit anti-Human, Mouse GKN2 Polyclonal Antibody | anti-GKN2 antibody

GKN2 Rabbit pAb

Gene Names
GKN2; GDDR; TFIZ1; PRO813; BRICD1B; VLTI465
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
GKN2; Polyclonal Antibody; GKN2 Rabbit pAb; GDDR; TFIZ1; PRO813; BRICD1B; VLTI465; anti-GKN2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Purity/Purification
Affinity purified
Form/Format
-20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Applicable Applications for anti-GKN2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:200-1:1000
Immunogen
Synthetic peptide of human GKN2
Conjugation
Unconjugated
Molecular Function
Gastrokine?2 is a putative gastric cancer?specific tumor suppressor gene, the loss of which is known to be involved in the development and progression of gastric cancer, and restoration of gastrokine?2 expression inhibits growth of gastric cancer cells in vitro. However, the underlying mechanism of these effects requires elucidation.
Modification
Unmodified
Cell Position
Secreted
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane: Mouse stomach tissue lysate, Primary antibody: 863004(GKN2 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes)

Western Blot (WB) (Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane: Mouse stomach tissue lysate, Primary antibody: 863004(GKN2 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes)

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 863004(GKN2 Antibody) at dilution 1/30. (Original magnification: ×200))

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 863004(GKN2 Antibody) at dilution 1/30. (Original magnification: ×200))
Product Categories/Family for anti-GKN2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18kDa
NCBI Official Full Name
gastrokine-2
NCBI Official Synonym Full Names
gastrokine 2
NCBI Official Symbol
GKN2
NCBI Official Synonym Symbols
GDDR; TFIZ1; PRO813; BRICD1B; VLTI465
NCBI Protein Information
gastrokine-2
UniProt Protein Name
Gastrokine-2
Protein Family
UniProt Gene Name
GKN2
UniProt Synonym Gene Names
BLOT; GDDR; TFIZ1
UniProt Entry Name
GKN2_HUMAN

NCBI Description

The secretory protein encoded by this gene is produced in gastric surface mucous cells, where it can bind trefoil factor family peptide 1 or gastrokine-1. This gene may be a tumor suppressor gene, as its expression is markedly decreased in gastric cancer tissues. The encoded protein interacts with gastrokine-1 and regulates homeostasis of the gastric mucosa. [provided by RefSeq, Dec 2015]

Uniprot Description

GKN2: Interacts with TFF2. Heterodimer with TFF1; disulfide linked.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 2p13.3

Cellular Component: extracellular region

Research Articles on GKN2

Similar Products

Product Notes

The GKN2 gkn2 (Catalog #AAA4758636) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GKN2 Rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GKN2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:200-1:1000. Researchers should empirically determine the suitability of the GKN2 gkn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GKN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.