Western Blot (WB)
(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Hela cells, A431 cells, Primary antibody: 856028(ZFYVE19 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds)
Rabbit anti-Human ZFYVE19 Polyclonal Antibody | anti-ZFYVE19 antibody
ZFYVE19 Rabbit pAb
Gene Names
ZFYVE19; ANCHR; MPFYVE
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
ZFYVE19; Polyclonal Antibody; ZFYVE19 Rabbit pAb; anti-ZFYVE19 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Purity/Purification
Affinity purified
Form/Format
-20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Applicable Applications for anti-ZFYVE19 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:500-1:2000
Immunogen
Synthetic peptide of human ZFYVE19
Conjugation
Unconjugated
Molecular Function
ZFYVE19 (zinc finger, FYVE domain containing 19), also known as MPFYVE (MLL partner containing FYVE domain), is a 471 amino acid protein that contains one FYVE-type zinc finger. Expressed in heart, brain, kidney, skeletal muscle and liver, ZFYVE19 may participate in transcriptional regulation events within the cell. Defects in the gene encoding ZFYVE19 are associated with acute myeloblastic leukemia (AML), a rapidly progressing cancer of the myeloid line of white blood cells that is characterized by fever, anemia, bone pain, shortness of breath and frequent infections. Three isoforms of ZFYVE19 exist due to alternative splicing events.
Modification
Unmodified
Cell Position
Cytoplasm, Cytoskeleton
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.
Western Blot (WB)
(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Hela cells, A431 cells, Primary antibody: 856028(ZFYVE19 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds)
Western Blot (WB)
(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Hela cells, A431 cells, Primary antibody: 856028(ZFYVE19 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds)
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using 856028(ZFYVE19 Antibody) at dilution 1/60. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using 856028(ZFYVE19 Antibody) at dilution 1/60. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 856028(ZFYVE19 Antibody) at dilution 1/60. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 856028(ZFYVE19 Antibody) at dilution 1/60. (Original magnification: ×200))
Product Categories/Family for anti-ZFYVE19 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51kDa
NCBI Official Full Name
abscission/NoCut checkpoint regulator isoform 1
NCBI Official Synonym Full Names
zinc finger FYVE-type containing 19
NCBI Official Symbol
ZFYVE19
NCBI Official Synonym Symbols
ANCHR; MPFYVE
NCBI Protein Information
abscission/NoCut checkpoint regulator
UniProt Protein Name
Zinc finger FYVE domain-containing protein 19
Protein Family
UniProt Gene Name
ZFYVE19
UniProt Synonym Gene Names
MPFYVE
UniProt Entry Name
ZFY19_HUMAN
Uniprot Description
ZFYVE19: A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML). Translocation t(11;15)(q23;q14) with MLL/HRX. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Oncoprotein
Chromosomal Location of Human Ortholog: 15q15.1
Cellular Component: centrosome; cytoplasm; midbody; cleavage furrow
Molecular Function: protein binding; zinc ion binding; phosphatidylinositol 3-phosphate binding
Biological Process: cell division; abscission; cell cycle; negative regulation of cytokinesis
Research Articles on ZFYVE19
Similar Products
Product Notes
The ZFYVE19 zfyve19 (Catalog #AAA4758226) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZFYVE19 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZFYVE19 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the ZFYVE19 zfyve19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZFYVE19, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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