Rabbit anti-Human ARL4A Polyclonal Antibody | anti-ARL4A antibody

ARL4A Rabbit pAb

Cat. Num. AAA4757891

• Gene Names: ARL4A; ARL4
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity purified
• Synonyms: ARL4A; Polyclonal Antibody; ARL4A Rabbit pAb; anti-ARL4A antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Purity/Purification: Affinity purified
• Form/Format: -20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

• Applicable Applications for anti-ARL4A antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
• Application Notes: WB: 1:200-1:1000
• Immunogen: Fusion protein of human ARL4A
• Conjugation: Unconjugated
• Molecular Function: ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guaninine nucleotide exchange rate. ARL4A is located in both the nuclear and extranuclear cell compartments. Multiple transcript variants encoding the same protein have been found for this gene
• Modification: Unmodified
• Cell Position: Cell membrane, Cytoplasm, Membrane, Nucleus
• Preparation and Storage: Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Gel: 10%SDS-PAGE, Lysate: 40 ug, Lane: Human fetal liver tissue, Primary antibody: 821698(ARL4A Antibody) at dilution 1/533, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds)

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 821698(ARL4A Antibody) at dilution 1/50. (Original magnification: ×200))

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human brain tissue using 821698(ARL4A Antibody) at dilution 1/50. (Original magnification: ×200))

Product Categories/Family for anti-ARL4A antibody

Primary antibody

NCBI and Uniprot Product Information

• NCBI GI #: 33876006
• NCBI GeneID: 10124
• UniProt Accession #: P40617; P80418; Q49AF5; A4D119
• Molecular Weight: 22,615 Da
• NCBI Official Full Name: Homo sapiens ADP-ribosylation factor-like 4A, mRNA
• NCBI Official Synonym Full Names: ADP ribosylation factor like GTPase 4A
• NCBI Official Symbol: ARL4A
• NCBI Official Synonym Symbols: ARL4
• NCBI Protein Information: ADP-ribosylation factor-like protein 4A
• UniProt Protein Name: ADP-ribosylation factor-like protein 4A
• Protein Family: ADP-ribosylation factor-like protein
• UniProt Gene Name: ARL4A
• UniProt Synonym Gene Names: ARL4
• UniProt Entry Name: ARL4A_HUMAN

NCBI Description

ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guaninine nucleotide exchange rate. ARL4A is located in both the nuclear and extranuclear cell compartments. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

ARL4A: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form. Belongs to the small GTPase superfamily. Arf family.

Protein type: G protein, monomeric; Nucleolus; G protein, monomeric, ARF

Chromosomal Location of Human Ortholog: 7p21.3

Cellular Component: cytoplasm; plasma membrane; nucleolus; nucleus

Molecular Function: protein binding; GTP binding

Biological Process: small GTPase mediated signal transduction; brown fat cell differentiation