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Western Blot (WB) (Western Blot analysis of MCF7 cells using IL-28 Polyclonal Antibody. Secondary antibody was diluted at 1:20000)

Rabbit anti-Human IL-28 Polyclonal Antibody | anti-IL-28 antibody

IL-28 Rabbit pAb

Gene Names
IFNL2; IL28A; IL-28A
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Affinity purified
Synonyms
IL-28; Polyclonal Antibody; IL-28 Rabbit pAb; Interleukin-28A; IL28A; IFNL2; ZCYTO20; IL-28A; Cytokine Zcyto20; Interferon lambda-2; IFN-lambda-2; anti-IL-28 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
IL-28 Polyclonal Antibody detects endogenous levels of IL-28 protein.
Purity/Purification
Affinity purified
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-IL-28 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
IHC-P: 1:100-1:300
ELISA: 1:20,000
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human IL28A. AA range:131-180
Conjugation
Unconjugated
Nucleotide Accession
282616
Modification
Unmodified
Cell Position
Secreted
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of MCF7 cells using IL-28 Polyclonal Antibody. Secondary antibody was diluted at 1:20000)

Western Blot (WB) (Western Blot analysis of MCF7 cells using IL-28 Polyclonal Antibody. Secondary antibody was diluted at 1:20000)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100)
Product Categories/Family for anti-IL-28 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,288 Da
NCBI Official Full Name
interferon lambda-2
NCBI Official Synonym Full Names
interferon, lambda 2
NCBI Official Symbol
IFNL2
NCBI Official Synonym Symbols
IL28A; IL-28A
NCBI Protein Information
interferon lambda-2; IFN-lambda-2; interleukin-28A; cytokine Zcyto20; interferon lambda 2; interferon-lambda 2; interleukin 28A (interferon, lambda 2)
UniProt Protein Name
Interferon lambda-2
UniProt Gene Name
IFNL2
UniProt Synonym Gene Names
IL28A; ZCYTO20; IFN-lambda-2; IL-28A
UniProt Entry Name
IFNL2_HUMAN

NCBI Description

This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]

Uniprot Description

IL28A: Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Belongs to the IL-28/IL-29 family.

Protein type: Secreted, signal peptide; Secreted; Cytokine

Chromosomal Location of Human Ortholog: 19q13.13

Cellular Component: extracellular space

Molecular Function: cytokine activity

Biological Process: positive regulation of immune response; mucosal immune response; JAK-STAT cascade; defense response to virus

Research Articles on IL-28

Similar Products

Product Notes

The IL-28 ifnl2 (Catalog #AAA4755050) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL-28 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL-28 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), ELISA (EIA). WB: 1:500-1:2000 IHC-P: 1:100-1:300 ELISA: 1:20,000. Researchers should empirically determine the suitability of the IL-28 ifnl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-28, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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