Western Blot (WB)
(Western blot analysis of SUZ12 expression in (1) HeLa cell lysate; (2) SW480 cell lysate.)
Rabbit SUZ12 Polyclonal Antibody | anti-SUZ12 antibody
Anti-SUZ12 Rabbit pAb
Gene Names
SUZ12; CHET9; JJAZ1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
Purity
Affinity Chromatography
Synonyms
SUZ12; Polyclonal Antibody; Anti-SUZ12 Rabbit pAb; anti-SUZ12 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
SUZ12 Antibody detects endogenous levels of total SUZ12
Purity/Purification
Affinity Chromatography
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
739
Applicable Applications for anti-SUZ12 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)
Application Notes
WB: 1:500-1:2000
ICC/IF: 1:50-1:200
IP: 1:50
ICC/IF: 1:50-1:200
IP: 1:50
Immunogen
A synthesized peptide derived from human SUZ12
Subcellular Location
Cytoplasm
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.
Western Blot (WB)
(Western blot analysis of SUZ12 expression in (1) HeLa cell lysate; (2) SW480 cell lysate.)
Western Blot (WB)
(Western blot analysis of SUZ12 expression in (1) HeLa cell lysate; (2) SW480 cell lysate.)
Related Product Information for anti-SUZ12 antibody
Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates ' Lys-9' (H3K9me) and ' Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
83kDa
NCBI Official Full Name
polycomb protein SUZ12 isoform 1
NCBI Official Synonym Full Names
SUZ12, polycomb repressive complex 2 subunit
NCBI Official Symbol
SUZ12
NCBI Official Synonym Symbols
CHET9; JJAZ1
NCBI Protein Information
polycomb protein SUZ12
UniProt Protein Name
Polycomb protein SUZ12
Protein Family
UniProt Gene Name
SUZ12
UniProt Synonym Gene Names
CHET9; JJAZ1; KIAA0160; ChET 9 protein
NCBI Description
This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. [provided by RefSeq, Jul 2009]
Uniprot Description
Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
Research Articles on SUZ12
Similar Products
Product Notes
The SUZ12 suz12 (Catalog #AAA4750292) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SUZ12 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SUZ12 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP). WB: 1:500-1:2000 ICC/IF: 1:50-1:200 IP: 1:50. Researchers should empirically determine the suitability of the SUZ12 suz12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SUZ12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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