Monkey Polymorphonuclear Elastase ELISA Kit | PMN elisa kit
Monkey Polymorphonuclear Elastase ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a tubulin binding cofactor that participates in microtubule dynamics. A mouse model of progressive motor neuropathy (pmn) was discovered to harbor a single amino acid deletion in this gene. Mice that are homozygous for pmn allele exhibit progressive atrophy and premature death due to respiratory failure. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Uniprot Description
TBCE: Tubulin-folding protein; involved in the second step of the tubulin folding pathway. Seems to be implicated in the maintenance of the neuronal microtubule network. Involved in regulation of tubulin heterodimer dissociation. Defects in TBCE are a cause of hypoparathyroidism- retardation-dysmorphism syndrome (HRD); also known as hypoparathyroidism with short stature, mental retardation, and seizures or Sanjad-Sakati syndrome. HRD is an autosomal recessive disorder reported almost exclusively in Middle Eastern populations. Defects in TBCE are the cause of Kenny-Caffey syndrome type 1 (KCS1). KCS1 is similar to HRD with the additional features of osteosclerosis and recurrent bacterial infections. Belongs to the TBCE family.
Protein type: Chaperone
Cellular Component: cytoskeleton; cytoplasm
Molecular Function: unfolded protein binding
Biological Process: tubulin folding; developmental growth; protein folding; axonogenesis; adult locomotory behavior; muscle atrophy; microtubule cytoskeleton organization and biogenesis; peripheral nervous system neuron axonogenesis; post-chaperonin tubulin folding pathway; post-embryonic development
Research Articles on PMN
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Product Notes
The Monkey PMN tbce (Catalog #AAA044341) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA044341 ELISA Kit recognizes Monkey PMN. It is sometimes possible for the material contained within the vial of "Polymorphonuclear Elastase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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