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ASIC1 blocking peptide

ASIC1 Immunizing Peptide

Gene Names
ASIC1; ASIC; ACCN2; BNaC2
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow
Synonyms
ASIC1; ASIC1 Immunizing Peptide; acid-sensing (proton-gated) ion channel 1; ACCN2; ASIC; BNaC2; Cation channel; amiloride-sensitive; neuronal; 2; acid-sensing ion channel 1; acid-sensing ion channel 1a protein; amiloride-sensitive cation channel 2; brain sodium channel 2; ASIC1 blocking peptide
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow
Form/Format
100ug of dried peptide
Sequence
C-NILPHHPARGT
Sequence Length
574
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
41
NCBI GenBank Nucleotide #
Molecular Weight
62,700 Da
NCBI Official Full Name
acid-sensing ion channel 1 isoform a
NCBI Official Synonym Full Names
acid sensing ion channel subunit 1
NCBI Official Symbol
ASIC1
NCBI Official Synonym Symbols
ASIC; ACCN2; BNaC2
NCBI Protein Information
acid-sensing ion channel 1
UniProt Protein Name
Acid-sensing ion channel 1
Protein Family
UniProt Gene Name
ASIC1
UniProt Synonym Gene Names
ACCN2; BNAC2; ASIC1; BNaC2
UniProt Entry Name
ASIC1_HUMAN

NCBI Description

This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]

Uniprot Description

ASIC1 iso1: non-voltage-gated amiloride-sensitive cation channel permeable for sodium, potassium and lithium. A member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Expressed in most if not all brain neurons.

Protein type: Channel, cation; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel

Chromosomal Location of Human Ortholog: 12q12

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: amiloride-sensitive sodium channel activity; protein binding

Biological Process: response to pH; sensory perception of sour taste; signal transduction; transport

Research Articles on ASIC1

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Product Notes

The ASIC1 asic1 (Catalog #AAA428652) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The ASIC1 Immunizing Peptide reacts with Human, Mouse, Rat, Dog, Pig, Cow and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-NILPHHPA RGT. It is sometimes possible for the material contained within the vial of "ASIC1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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