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Tfb2m blocking peptide

Tfb2m Immunizing Peptide

Gene Names
Tfb2m; Hkp1
Reactivity
Mouse, Rat
Synonyms
Tfb2m; Tfb2m Immunizing Peptide; transcription factor B2; mitochondrial; Hkp1; OTTMUSP00000025719; S-adenosylmethionine-6-N'; N'-adenosyl(rRNA) dimethyltransferase 2; dimethyladenosine transferase 2; house-keeping protein 1; mTFB2M; mitochondrial 12S rRNA dimethylas; Tfb2m (mouse); Tfb2m blocking peptide
Ordering
For Research Use Only!
Reactivity
Mouse, Rat
Form/Format
100ug of dried peptide
Sequence
C-RNLVRDLLEHQNPS
Sequence Length
396
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45,864 Da
NCBI Official Full Name
dimethyladenosine transferase 2, mitochondrial
NCBI Official Synonym Full Names
transcription factor B2, mitochondrial
NCBI Official Symbol
Tfb2m
NCBI Official Synonym Symbols
Hkp1
NCBI Protein Information
dimethyladenosine transferase 2, mitochondrial
UniProt Protein Name
Dimethyladenosine transferase 2, mitochondrial
UniProt Gene Name
Tfb2m
UniProt Synonym Gene Names
mTFB2M; mtTFB2
UniProt Entry Name
TFB2M_MOUSE

Uniprot Description

TFB2M: S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity. Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily.

Protein type: Methyltransferase; EC 2.1.1.-; Transcription, coactivator/corepressor

Cellular Component: cell junction; mitochondrial matrix; mitochondrion

Molecular Function: 1-phenanthrol methyltransferase activity; 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity; arginine N-methyltransferase activity; C-methyltransferase activity; C-terminal protein carboxyl methyltransferase activity; cobalt-precorrin-3 C17-methyltransferase activity; cobalt-precorrin-5B C1-methyltransferase activity; cobalt-precorrin-6B C5-methyltransferase activity; cobalt-precorrin-7 C15-methyltransferase activity; demethylmenaquinone methyltransferase activity; dimethylamine methyltransferase activity; DNA-methyltransferase activity; hydroxyneurosporene-O-methyltransferase activity; lysine N-methyltransferase activity; methanol-specific methylcobalamin:coenzyme M methyltransferase activity; methylamine-specific methylcobalamin:coenzyme M methyltransferase activity; methylarsonite methyltransferase activity; methyltransferase activity; monomethylamine methyltransferase activity; mRNA methyltransferase activity; N-methyltransferase activity; O-methyltransferase activity; protein methyltransferase activity; protein-arginine N-methyltransferase activity; protein-arginine N5-methyltransferase activity; protein-leucine O-methyltransferase activity; protein-lysine N-methyltransferase activity; RNA binding; RNA methyltransferase activity; rRNA (adenine) methyltransferase activity; rRNA (adenine-N6,N6-)-dimethyltransferase activity; rRNA (adenine-N6-)-methyltransferase activity; rRNA (cytosine) methyltransferase activity; rRNA (cytosine-C5-967)-methyltransferase activity; rRNA (guanine) methyltransferase activity; rRNA (uridine) methyltransferase activity; rRNA (uridine-2'-O-)-methyltransferase activity; rRNA methyltransferase activity; S-methyltransferase activity; selenocysteine methyltransferase activity; transcription cofactor activity; transferase activity; trimethylamine methyltransferase activity; tRNA (adenine)-methyltransferase activity; tRNA (adenine-57, 58-N(1)-) methyltransferase activity; tRNA (adenine-N1-)-methyltransferase activity; tRNA (cytosine)-methyltransferase activity; tRNA (cytosine-5-)-methyltransferase activity; tRNA (guanine) methyltransferase activity; tRNA (guanine-N1-)-methyltransferase activity; tRNA (guanine-N2-)-methyltransferase activity; tRNA (uracil) methyltransferase activity; tRNA methyltransferase activity

Biological Process: methylation; positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent; rRNA methylation; rRNA processing; transcription from mitochondrial promoter; transcription initiation from mitochondrial promoter; transcription, DNA-dependent

Research Articles on Tfb2m

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Product Notes

The Tfb2m tfb2m (Catalog #AAA427535) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The Tfb2m Immunizing Peptide reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-RNLVRDLL EHQNPS. It is sometimes possible for the material contained within the vial of "Tfb2m, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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