AGTPBP1 / NNA1 Blocking Peptide | AGTPBP1 blocking peptide
AGTPBP1 / NNA1 Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
NNA1 is a zinc carboxypeptidase that contains nuclear localization signals and an ATP/GTP-binding motif that was initially cloned from regenerating spinal cord neurons of the mouse.[supplied by OMIM, Jul 2002]
Uniprot Description
Nna1: Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. Interacts with MYLK. Belongs to the peptidase M14 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.17.-; Protease
Chromosomal Location of Human Ortholog: 9q21.33
Cellular Component: cytoplasm; cytosol; mitochondrion; nucleus
Molecular Function: metallocarboxypeptidase activity; tubulin binding; zinc ion binding
Biological Process: cerebellar Purkinje cell differentiation; eye photoreceptor cell differentiation; mitochondrion organization and biogenesis; neuromuscular process; olfactory bulb development; proteolysis
Research Articles on AGTPBP1
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Product Notes
The AGTPBP1 agtpbp1 (Catalog #AAA427513) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The AGTPBP1 / NNA1 Immunizing Peptide reacts with Human, Mouse, Rat, Dog, Cow and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-TSPLEYNL PS. It is sometimes possible for the material contained within the vial of "AGTPBP1 / NNA1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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