SEPT7 blocking peptide
SEPT7 Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. [provided by RefSeq, Jul 2011]
Uniprot Description
SEPT7: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Belongs to the septin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Hydrolase; Cytoskeletal; Cell cycle regulation
Chromosomal Location of Human Ortholog: 7p14.2
Cellular Component: actin cytoskeleton; apical plasma membrane; axoneme; cleavage furrow; cytoplasm; cytosol; microtubule cytoskeleton; midbody; nonmotile primary cilium; nucleolus; nucleus; plasma membrane; spindle; stress fiber
Molecular Function: GTP binding; identical protein binding; protein binding; structural molecule activity
Biological Process: cytokinesis; mitosis; protein heterooligomerization; shape changes of embryonic cells
Research Articles on SEPT7
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Product Notes
The SEPT7 sept7 (Catalog #AAA426798) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The SEPT7 Immunizing Peptide reacts with Human, Mouse, Rat, Dog, Pig, Cow, Horse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-DNNKNKGQ LTKSP. It is sometimes possible for the material contained within the vial of "SEPT7, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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