DDAH2 blocking peptide
DDAH2 Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a dimethylarginine dimethylaminohydrolase. The encoded enzyme functions in nitric oxide generation by regulating the cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. The protein may be localized to the mitochondria. Alternative splicing resulting in multiple transcript variants. [provided by RefSeq, Dec 2014]
Uniprot Description
DDAH2: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. Belongs to the DDAH family.
Protein type: Apoptosis; EC 3.5.3.18; Hydrolase
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: centrosome; cytoplasm; cytosol; mitochondrion
Molecular Function: amino acid binding; catalytic activity; dimethylargininase activity; protein binding
Biological Process: arginine catabolic process; citrulline metabolic process; negative regulation of apoptosis; nitric oxide biosynthetic process; nitric oxide mediated signal transduction; positive regulation of nitric oxide biosynthetic process; regulation of nitric-oxide synthase activity
Research Articles on DDAH2
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Product Notes
The DDAH2 ddah2 (Catalog #AAA426690) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The DDAH2 Immunizing Peptide reacts with Human, Mouse, Rat, Dog, Cow and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: SSLCLVLSTR PHS. It is sometimes possible for the material contained within the vial of "DDAH2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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