PCBP4 blocking peptide
PCBP4 Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
PCBP4: Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 3p21
Cellular Component: cytosol; ribonucleoprotein complex
Molecular Function: DNA binding; mRNA 3'-UTR binding; RNA binding
Biological Process: DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; regulation of mRNA stability
Research Articles on PCBP4
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Product Notes
The PCBP4 pcbp4 (Catalog #AAA425939) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The PCBP4 Immunizing Peptide reacts with Human, Mouse, Rat, Dog and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-NGSKKAER QKFSPY. It is sometimes possible for the material contained within the vial of "PCBP4, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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