Goat LSM3 Polyclonal Antibody | anti-LSM3 antibody

Goat anti-LSM3 Antibody

Cat. Num. AAA423172

• Gene Names: LSM3; SMX4; USS2; YLR438C
• Reactivity: Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow
• Applications: ELISA
• Purity: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Synonyms: LSM3; Polyclonal Antibody; Goat anti-LSM3 Antibody; LSM3 homolog; U6 small nuclear RNA associated (S. cerevisiae); SMX4; USS2; YLR438C; OTTHUMP00000160275; U6 snRNA-associated Sm-like protein LSm3; LSM3 antibody; U6 small nuclear RNA associated (S. cerevisiae) antibody; OTTHUMP00000160275 antibody; SMX4 antibody; U6 snRNA-associated Sm-like protein LSm3 antibody; USS2 antibody; YLR438C antibody; anti-LSM3 antibody

• Host: Goat
• Reactivity: Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow
• Clonality: Polyclonal
• Purity/Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Form/Format: Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: 100ug specific antibody in 200ul (varies by lot)
• Sequence: SLDERIYVKMRND
• Sequence Length: 102

• Applicable Applications for anti-LSM3 antibody: Peptide ELISA (EIA)
• Application Notes: Peptide ELISA: Antibody detection limit dilution 1: 128000.; Western Blot: Preliminary experiments in Human and Rodent Spleen lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).
• Immunogen: Peptide with sequence C-SLDERIYVKMRND, from the internal region of the protein sequence according to NP_055278.1.
• Epitope: Internal region
• Preparation and Storage: Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

• NCBI GI #: 7657315
• NCBI GeneID: 27258
• NCBI Accession #: NP_055278.1
• NCBI GenBank Nucleotide #: NM_014463.2
• Molecular Weight: 11,845 Da
• NCBI Official Full Name: U6 snRNA-associated Sm-like protein LSm3
• NCBI Official Synonym Full Names: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
• NCBI Official Symbol: LSM3
• NCBI Official Synonym Symbols: SMX4; USS2; YLR438C
• NCBI Protein Information: U6 snRNA-associated Sm-like protein LSm3
• UniProt Protein Name: U6 snRNA-associated Sm-like protein LSm3
• Protein Family: U6 snRNA-associated Sm-like protein
• UniProt Gene Name: LSM3
• UniProt Entry Name: LSM3_HUMAN

NCBI Description

Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004]

Uniprot Description

LSM3: Binds specifically to the 3'-terminal U-tract of U6 snRNA. Belongs to the snRNP Sm proteins family.

Protein type: Spliceosome; RNA splicing; RNA-binding

Chromosomal Location of Human Ortholog: 3p25.1

Cellular Component: cytosol; nucleoplasm; nucleus; U4/U6 x U5 tri-snRNP complex

Molecular Function: protein binding; RNA binding

Biological Process: cytoplasmic mRNA processing body assembly; mRNA processing; nuclear mRNA splicing, via spliceosome