Goat KIF26B Polyclonal Antibody | anti-KIF26B antibody

Goat anti-KIF26B Antibody

Cat. Num. AAA422439

• Reactivity: Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
• Applications: ELISA
• Purity: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Synonyms: KIF26B; Polyclonal Antibody; Goat anti-KIF26B Antibody; kinesin family member 26B; FLJ10157; MGC35030; FLJ10157 antibody; kinesin family member 26B antibody; MGC35030 antibody; KIF26B antibody; anti-KIF26B antibody

• Host: Goat
• Reactivity: Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
• Clonality: Polyclonal
• Purity/Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Form/Format: Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: 100ug specific antibody in 200ul (varies by lot)
• Sequence: SHYECLSLER
• Sequence Length: 2108

• Applicable Applications for anti-KIF26B antibody: Peptide ELISA (EIA)
• Application Notes: Peptide ELISA: Antibody detection limit dilution 1: 16000.; Western Blot: Preliminary experiments in Human Brain (Cerebellum), Heart and Liver lysates gave no specific signal but low background (at antibody concentration up to 2ug/ml).
• Immunogen: Peptide with sequence SHYECLSLER, from the internal region of the protein sequence according to NP_060482.2.
• Epitope: Internal region
• Preparation and Storage: Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

• NCBI GI #: 124430752
• NCBI GeneID: 55083
• NCBI Accession #: NP_060482.2
• NCBI GenBank Nucleotide #: NM_018012.3
• Molecular Weight: 184,420 Da
• NCBI Official Full Name: kinesin-like protein KIF26B
• NCBI Official Synonym Full Names: kinesin family member 26B
• NCBI Official Symbol: KIF26B
• NCBI Protein Information: kinesin-like protein KIF26B
• UniProt Protein Name: Kinesin-like protein KIF26B
• Protein Family: Kinesin-like protein
• UniProt Gene Name: KIF26B
• UniProt Entry Name: KI26B_HUMAN

Uniprot Description

KIF26B: Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction. Belongs to the kinesin-like protein family. KIF26 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motor; Microtubule-binding

Chromosomal Location of Human Ortholog: 1q44

Cellular Component: cytoplasm; kinesin complex; microtubule

Molecular Function: ATP binding; microtubule binding; plus-end-directed microtubule motor activity

Biological Process: axon guidance; cytoskeleton-dependent intracellular transport; establishment of cell polarity; metabolic process; microtubule-based movement; positive regulation of cell-cell adhesion; protein localization