Goat TRAF3IP1 Polyclonal Antibody | anti-TRAF3IP1 antibody

Goat anti-TRAF3IP1 Antibody

Cat. Num. AAA421944

• Gene Names: TRAF3IP1; IFT54; MIPT3; SLSN9; MIP-T3
• Reactivity: Expected from sequence similarity: Human
• Applications: ELISA
• Purity: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Synonyms: TRAF3IP1; Polyclonal Antibody; Goat anti-TRAF3IP1 Antibody; TNF receptor-associated factor 3 interacting protein 1; DKFZp434F124; MIP-T3; MIPT3; interleukin 13 receptor alpha 1-binding protein-1; microtubule interacting protein that associates with TRAF3; TRAF3IP1 antibody; TNF receptor-associated factor 3 interacting protein 1 antibody; DKFZp434F124 antibody; MIP-T3 antibody; MIPT3 antibody; interleukin 13 receptor alpha 1-binding protein-1 antibody; microtubule interacting protein that associates with TRAF3 antibody; anti-TRAF3IP1 antibody

• Host: Goat
• Reactivity: Expected from sequence similarity: Human
• Clonality: Polyclonal
• Purity/Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Form/Format: Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: 100ug specific antibody in 200ul (varies by lot)
• Sequence: RCENIQPNPTEKQK
• Sequence Length: 691

• Applicable Applications for anti-TRAF3IP1 antibody: Peptide ELISA (EIA)
• Application Notes: Peptide ELISA: Antibody detection limit dilution 1: 32000.; Western Blot: Preliminary experiments in Human Bone Marrow, Heart, Testis and Thyroid Gland lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).
• Immunogen: Peptide with sequence RCENIQPNPTEKQK, from the internal region of the protein sequence according to NP_056465.2.
• Epitope: Internal region
• Preparation and Storage: Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

• NCBI GI #: 20070262
• NCBI GeneID: 26146
• NCBI Accession #: NP_056465.2
• NCBI GenBank Nucleotide #: NM_015650.3
• Molecular Weight: 71,529 Da
• NCBI Official Full Name: TRAF3-interacting protein 1 isoform 1
• NCBI Official Synonym Full Names: TRAF3 interacting protein 1
• NCBI Official Symbol: TRAF3IP1
• NCBI Official Synonym Symbols: IFT54; MIPT3; SLSN9; MIP-T3
• NCBI Protein Information: TRAF3-interacting protein 1
• UniProt Protein Name: TRAF3-interacting protein 1
• Protein Family: TRAF3-interacting protein
• UniProt Gene Name: TRAF3IP1
• UniProt Synonym Gene Names: IFT54; MIPT3; MIP-T3
• UniProt Entry Name: MIPT3_HUMAN

Uniprot Description

TRAF3IP1: Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Belongs to the TRAF3IP1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Microtubule-binding

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: axoneme; centrosome; cytoplasm

Molecular Function: microtubule binding; protein binding

Biological Process: cilium biogenesis; embryonic camera-type eye development; embryonic digit morphogenesis; embryonic heart tube development; intraflagellar transport; kidney development; morphogenesis of a polarized epithelium; negative regulation of defense response to virus; negative regulation of interferon type I production; negative regulation of interferon-beta production; negative regulation of protein amino acid phosphorylation; negative regulation of protein complex assembly; neural tube patterning