Western Blot (WB)
((1ug/ml) staining of Mouse Spleen lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat APOBEC1 Polyclonal Antibody | anti-APOBEC1 antibody
Goat anti-APOBEC1 Antibody
Western Blot: Approx.28kDa band observed in Mouse Spleen lysates (calculated MW of 28.2kDa according to Human NP_001635.2 and 27.5kDa acccording to Mouse NP_112436.1). Recommended concentration: 1-3ug/ml.
Western Blot (WB)
((1ug/ml) staining of Mouse Spleen lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((1ug/ml) staining of Mouse Spleen lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015]
Uniprot Description
APOBEC1: apolipoprotein B mRNA editing enzyme. Responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. Expressed exclusively in the small intestine.
Protein type: Cell cycle regulation; RNA processing; Hydrolase; RNA-binding; EC 3.5.4.-
Chromosomal Location of Human Ortholog: 12p13.1
Cellular Component: cytoplasm; nucleoplasm
Molecular Function: AU-rich element binding; cytidine deaminase activity; cytosine deaminase activity; enzyme activator activity; mRNA binding; protein binding; protein domain specific binding; ribonucleoprotein binding; RNA binding; zinc ion binding
Biological Process: cellular response to insulin stimulus; cytidine deamination; cytidine to uridine editing; defense response to virus; lipid metabolic process; lipoprotein biosynthetic process; lipoprotein transport; mRNA modification; mRNA processing; mRNA stabilization; positive regulation of catalytic activity; regulation of cell proliferation; response to calcium ion; response to drug; response to ethanol; response to gamma radiation; response to osmotic stress; response to zinc ion; RNA processing
Research Articles on APOBEC1
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Product Notes
The APOBEC1 apobec1 (Catalog #AAA421886) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-APOBEC1 Antibody reacts with Tested: Mouse; Expected from sequence similarity: Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's APOBEC1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Approx.28kDa band observed in Mouse Spleen lysates (calculated MW of 28.2kDa according to Human NP_001635.2 and 27.5kDa acccording to Mouse NP_112436.1). Recommended concentration: 1-3ug/ml. Researchers should empirically determine the suitability of the APOBEC1 apobec1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: DVFYDPRELR KEAC. It is sometimes possible for the material contained within the vial of "APOBEC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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