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Western Blot (WB) (Staining (0.5ug/ml) of human lymph node lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.)

Goat GIPC3 Polyclonal Antibody | anti-GIPC3 antibody

Goat anti-GIPC3 Antibody

Gene Names
GIPC3; DFNB15; DFNB72; DFNB95; C19orf64
Reactivity
Tested: Human; Expected from sequence similarity: Human
Applications
ELISA, Western Blot
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
GIPC3; Polyclonal Antibody; Goat anti-GIPC3 Antibody; PDZ domain protein GIPC3; GIPC PDZ domain containing family; member 3; C19orf64; DKFZp686J1198; FLJ40925; GIPC3 antibody; PDZ domain protein GIPC3 antibody; member 3 antibody; C19orf64 antibody; DKFZp686J1198 antibody; FLJ40925 antibody; anti-GIPC3 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Tested: Human; Expected from sequence similarity: Human
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
EGAAAREARGTET
Sequence Length
312
Applicable Applications for anti-GIPC3 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Approx 40kDa band observed in human lymph node lysates (predicted MW of 36kDa according to NP_573568). Recommended for use at 0.2-1.5ug/ml.
Immunogen
Peptide with sequence EGAAAREARGTET-C, from the N Terminus of the protein sequence according to NP_573568.1.
Epitope
N Terminus
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

Western Blot (WB)

(Staining (0.5ug/ml) of human lymph node lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.)

Western Blot (WB) (Staining (0.5ug/ml) of human lymph node lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
33,982 Da
NCBI Official Full Name
PDZ domain-containing protein GIPC3
NCBI Official Synonym Full Names
GIPC PDZ domain containing family member 3
NCBI Official Symbol
GIPC3
NCBI Official Synonym Symbols
DFNB15; DFNB72; DFNB95; C19orf64
NCBI Protein Information
PDZ domain-containing protein GIPC3
UniProt Protein Name
PDZ domain-containing protein GIPC3
UniProt Gene Name
GIPC3
UniProt Synonym Gene Names
C19orf64
UniProt Entry Name
GIPC3_HUMAN

NCBI Description

The protein encoded by this gene belongs to the GIPC family. Studies in mice suggest that this gene is required for postnatal maturation of the hair bundle and long-term survival of hair cells and spiral ganglion in the ear. Mutations in this gene are associated with autosomal recessive deafness. [provided by RefSeq, Dec 2011]

Uniprot Description

GIPC3: Required for postnatal maturation of the hair bundle and long-term survival of hair cells and spiral ganglion. Defects in GIPC3 are the cause of deafness autosomal recessive type 15 (DFNB15). A form of non-syndromic sensorineural hearing loss with prelingual onset. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Belongs to the GIPC family.

Chromosomal Location of Human Ortholog: 19p13.3

Disease: Deafness, Autosomal Recessive 15

Research Articles on GIPC3

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Product Notes

The GIPC3 gipc3 (Catalog #AAA421450) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-GIPC3 Antibody reacts with Tested: Human; Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's GIPC3 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Approx 40kDa band observed in human lymph node lysates (predicted MW of 36kDa according to NP_573568). Recommended for use at 0.2-1.5ug/ml. Researchers should empirically determine the suitability of the GIPC3 gipc3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: EGAAAREARG TET. It is sometimes possible for the material contained within the vial of "GIPC3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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