Goat ORP11/OSBPL11 Polyclonal Antibody | anti-OSBPL11 antibody

Goat anti-ORP11/OSBPL11 Antibody

Cat. Num. AAA421442

• Gene Names: OSBPL11; ORP11; ORP-11; OSBP12; TCCCIA00292
• Reactivity: Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
• Applications: ELISA, Western Blot
• Purity: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Synonyms: ORP11/OSBPL11; Polyclonal Antibody; Goat anti-ORP11/OSBPL11 Antibody; OSBPL11; ORP11; ORP-11; OSBP12; FLJ13012; FLJ13164; TCCCIA00292; oxysterol binding protein-like 11; OSBP-related protein 11; oxysterol-binding protein-related protein 11; OSBPL11 antibody; ORP11 antibody; ORP-11 antibody; OSBP12 antibody; FLJ13012 antibody; FLJ13164 antibody; TCCCIA00292 antibody; oxysterol binding protein-like 11 antibody; OSBP-related protein 11 antibody; oxysterol-binding protein-related protein 11 antibody; ORP11 / OSBPL11; anti-OSBPL11 antibody

• Host: Goat
• Reactivity: Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
• Clonality: Polyclonal
• Purity/Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Form/Format: Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: 100ug specific antibody in 200ul (varies by lot)
• Sequence: KPLWKIIPTTQPAE
• Sequence Length: 747

• Applicable Applications for anti-OSBPL11 antibody: Peptide ELISA (EIA), Western Blot (WB)
• Application Notes: Peptide ELISA: Antibody detection limit dilution 1: 16000.; Western Blot: Approx 85-90kDa band observed in Human Brain lysates (predicted MWs of 86kDa according to NP_073613). A minor band of unknown identity was also consistently observed at 75kDa. Recommended for use at 1-2ug/ml.
• Immunogen: Peptide with sequence C-KPLWKIIPTTQPAE, from the C Terminus of the protein sequence according to NP_073613.2.
• Epitope: C Terminus
• Preparation and Storage: Aliquot and store at -20 degree C. Minimize freezing and thawing.

Western Blot (WB)

(Staining (1ug/ml) of Human Brain lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.)

NCBI and Uniprot Product Information

• NCBI GI #: 19923592
• NCBI GeneID: 114885
• NCBI Accession #: NP_073613.2
• NCBI GenBank Nucleotide #: NM_022776.4
• Molecular Weight: 83,643 Da
• NCBI Official Full Name: oxysterol-binding protein-related protein 11
• NCBI Official Synonym Full Names: oxysterol binding protein like 11
• NCBI Official Symbol: OSBPL11
• NCBI Official Synonym Symbols: ORP11; ORP-11; OSBP12; TCCCIA00292
• NCBI Protein Information: oxysterol-binding protein-related protein 11
• UniProt Protein Name: Oxysterol-binding protein-related protein 11
• Protein Family: Oxysterol-binding protein-related protein
• UniProt Gene Name: OSBPL11
• UniProt Synonym Gene Names: ORP11; OSBP12; ORP-11; OSBP-related protein 11
• UniProt Entry Name: OSB11_HUMAN

NCBI Description

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. [provided by RefSeq, Jul 2008]

Uniprot Description

OSBPL11: a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 3q21

Cellular Component: Golgi apparatus; late endosome membrane

Molecular Function: lipid binding

Biological Process: fat cell differentiation; lipid transport