Rat anti-Mouse Sell/CD62L Monoclonal Antibody | anti-CD62L antibody
Anti-mouse Sell/CD62L Monoclonal Antibody
Reactivity
Mouse
Purity
Affinity Purified
Synonyms
Sell/CD62L; Monoclonal Antibody; Anti-mouse Sell/CD62L Monoclonal Antibody; anti-CD62L antibody
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Specificity
The antibody is specific for a 90000 dalton lymphocyte surface receptor (murine equivalent to human L-selectin/CD62L) for high endothelial venule determinants in peripheral lymph nodes. This receptor appears to be required for lymphocyte homing into lymph nodes in vivo. The antibody binds to a determinant present in a peptide containing the 13 C terminal residues of ubiquitin. It does not bind to native ubiquitin or to ubiquitinated proteins.
Purity/Purification
Affinity Purified
Form/Format
Liquid
Concentration
100ug/100ul (varies by lot)
Immunogen
38C-13 cells (a B cell lymphoma cell line derived from a C3H/eb mouse)
Storage Buffer
PBS, pH 7.4 with 0.02% sodium azide.
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Related Product Information for anti-CD62L antibody
CD62L, L-selectin, is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins.
References
Gallatin WM, et al. A cell-surface molecule involved in organ-specific homing of lymphocytes. Nature 304: 30-34, 1983. Siegelman M, et al. Cell surface molecule associated with lymphocyte homing is a ubiquitinated branched-chain glycoprotein. Science 231: 823-829, 1986. Wilson ME, et al. Local suppression of IFN-gamma in hepatic granulomas correlates with tissue-specific replication of Leishmania chagasi. J. Immunol. 156: 2231-2239, 1996.
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Product Notes
The CD62L (Catalog #AAA418464) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti-mouse Sell/CD62L Monoclonal Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Sell/CD62L, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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