Immunohistochemistry (IHC)
Rabbit NOTCH4 Polyclonal Antibody | anti-NOTCH4 antibody
Anti-NOTCH4 Antibody
Reactivity
Human. Not yet tested in other species
Applications
ELISA, Immunohistochemistry
Purity
Affinity purified
Synonyms
NOTCH4; Polyclonal Antibody; Anti-NOTCH4 Antibody; anti-NOTCH4 antibody
Host
Rabbit
Reactivity
Human. Not yet tested in other species
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
Liquid
Concentration
100ug/100ul (varies by lot)
Applicable Applications for anti-NOTCH4 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Peptide ELISA titer: 1:5,000-1:20,000
Immunohistochemistry: 1:50-200
Optimal dilutions/concentrations should be determined by the end user
Immunohistochemistry: 1:50-200
Optimal dilutions/concentrations should be determined by the end user
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Rabbit polyclonal NOTCH4 antibody was raised against a peptide from the C terminal residues of human NOTCH4.
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Immunohistochemistry (IHC)
Immunohistochemistry (IHC)
Related Product Information for anti-NOTCH4 antibody
This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008]
References
(1) Read,R.C., Teare,D.M., Pridmore,A.C., et al.The tumor necrosis factor polymorphism TNF (-308) is associated with susceptibility to meningococcal sepsis, but not with lethality. Crit. Care Med. 37 (4), 1237-1243 (2009)
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Product Notes
The NOTCH4 (Catalog #AAA416287) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-NOTCH4 Antibody reacts with Human. Not yet tested in other species and may cross-react with other species as described in the data sheet. AAA Biotech's NOTCH4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Peptide ELISA titer: 1:5,000-1:20,000 Immunohistochemistry: 1:50-200 Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the NOTCH4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NOTCH4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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