CAMKK1 active protein
Recombinant Rat CAMKK1 (N-GST tag)
Purity
70%-90%
Synonyms
CAMKK1; Recombinant Rat CAMKK1 (N-GST tag); CaMKK1; CaMKK alpha; CaM-kinase IV kinase; CAMKK1 active protein
Host
Insect Cells
Purity/Purification
70%-90%
Form/Format
Liquid; 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Sequence Length
3406
Bioactivity
The specific activity of CAMKK1 was determined to be 9 nmol/min/mg as per activity assay protocol.
Preparation and Storage
Store product at-70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature.
For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Related Product Information for CAMKK1 active protein
CAMKK1 or CAMKKalpha is a Ca(2+)/calmodulin-dependent protein kinase that activates CAM-kinases I and IV via phosphorylation of their Thr(177) and Thr(196) residues, respectively. Recent studies have shown that the activity of CAMKK1 is decreased upon phosphorylation by cAMP-dependent protein kinase (PKA) The CAMKKalpha has been identified in intact cells as AMPKKs, predicting a significant role for this kinase in regulating AMPK activity in vivo. It has been shown that 2-deoxyglucose-and ionomycin-stimulated AMPK activity is substantially reduced in HeLa cells transfected with small interfering RNAs specific for CAMKKalpha.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
88.0 kDa
NCBI Official Full Name
Rattus norvegicus Ca2+/calmodulin-dependent protein kinase kinase mRNA, complete cds
NCBI Official Synonym Full Names
calcium/calmodulin-dependent protein kinase kinase 1
NCBI Official Symbol
Camkk1
NCBI Protein Information
calcium/calmodulin-dependent protein kinase kinase 1
Protein Family
NCBI Description
catalyzes the activation of Ca+2/calmodulin-dependent protein kinases CaM-kinases I and IV [RGD, Feb 2006]
Research Articles on CAMKK1
Similar Products
Product Notes
The CAMKK1 (Catalog #AAA4160420) is an Active Protein produced from Insect Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CAMKK1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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