Testing Data
Rabbit anti-Mouse, Rat p47Phox Polyclonal Antibody | anti-p47Phox antibody
Anti-p47Phox Antibody
Western blot analysis: 1:200-500
Optimal dilutions/concentrations should be determined by the end user.
Testing Data
Testing Data
NCBI and Uniprot Product Information
Uniprot Description
p47phox: the 47-kilodalton cytosolic subunit of the multi-protein complex known as NADPH oxidase found in neutrophils. The holo-oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Contains 2 SH2 domains. Mutations in NCF1, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease.
Protein type: Oxidoreductase; EC 1.-.-.-
Cellular Component: Golgi apparatus; extrinsic to membrane; rough endoplasmic reticulum; membrane; cell soma; cytoplasm; dendrite; plasma membrane; cytosol; NADPH oxidase complex
Molecular Function: protein binding; superoxide-generating NADPH oxidase activity; phosphatidylinositol-3,4-bisphosphate binding; lipid binding; SH3 domain binding; phosphoinositide binding
Biological Process: respiratory burst during defense response; respiratory burst; NADP catabolic process; apoptosis; leukocyte mediated cytotoxicity; leukotriene metabolic process; cell proliferation; defense response to Gram-positive bacterium; response to bacterium; negative regulation of smooth muscle contraction; defense response to bacterium; cellular defense response; response to yeast; inflammatory response; protein targeting to membrane; defense response to fungus; superoxide release; hydrogen peroxide biosynthetic process
Research Articles on p47Phox
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Product Notes
The p47Phox ncf1 (Catalog #AAA415556) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-p47Phox Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's p47Phox can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Peptide ELISA titer: 1:5,000-1:20,000 Western blot analysis: 1:200-500 Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the p47Phox ncf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p47Phox, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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