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Prostate Specific Antigen Active Protein | PSA active protein

Prostate Specific Antigen, Human

Gene Names
KLK3; APS; PSA; hK3; KLK2A1
Purity
>/= 95% by SDS-PAGE
Synonyms
Prostate Specific Antigen; Human; PSA active protein
Ordering
For Research Use Only!
Host
Human Seminal Fluid
Purity/Purification
>/= 95% by SDS-PAGE
Form/Format
Lyophilized from 50mM Ammonium Bicarbonate and low Endotoxin.
White to off white.
Sequence Length
227
Grade
High Purity
Activity
= 1.1 mg/mg by Accubind ELISA
Reconstitution
Reconstitute using neutral pH buffer of choice.
Preparation and Storage
Store at -2-8°C for short term storage, -20°C for long term storage after reconstitution. Avoid freeze/thaw cycles

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
354
UniProt Accession #
Molecular Weight
Approximately 34kDa
NCBI Official Full Name
prostate specific antigen
NCBI Official Synonym Full Names
kallikrein related peptidase 3
NCBI Official Symbol
KLK3
NCBI Official Synonym Symbols
APS; PSA; hK3; KLK2A1
NCBI Protein Information
prostate-specific antigen
UniProt Protein Name
Prostate-specific antigen
UniProt Gene Name
KLK3
UniProt Synonym Gene Names
APS; PSA; Seminin

NCBI Description

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.

Research Articles on PSA

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Product Notes

The PSA klk3 (Catalog #AAA382010) is an Active Protein produced from Human Seminal Fluid and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Prostate Specific Antigen, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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