Western Blot (WB)
(Western blot analysis GCFC1 using Jurkat whole cell lysates)
Rabbit anti-Human, Mouse GCFC1 Polyclonal Antibody | anti-GCFC1 antibody
GCFC1 Antibody
Gene Names
PAXBP1; GCFC; BM020; GCFC1; FSAP105; C21orf66
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
GCFC1; Polyclonal Antibody; GCFC1 Antibody; BM 020; BM020; Chromosome 21 open reading frame 66; FSAP105; Functional spliceosome-associated protein 105; GC rich sequence DNA binding factor candidate; GC-rich sequence DNA-binding factor 1; GCFC; GCFC1_HUMAN; PAX3 and PAX7 binding protein 1; PAXBP1; anti-GCFC1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
GCFC1 antibody detects endogenous levels of total GCFC1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
815
Applicable Applications for anti-GCFC1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human GCFC1
Subcellular Location
Nucleus.
Tissue Specificity
Ubiquitous.
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Similarity
Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis GCFC1 using Jurkat whole cell lysates)
Western Blot (WB)
(Western blot analysis GCFC1 using Jurkat whole cell lysates)
Related Product Information for anti-GCFC1 antibody
Function: Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of 'Lys-4' of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20 (By similarity).
Subunit Structure: Interacts with PAX3 and PAX7. Interacts with WDR5; associates with a histone methyltransferase (HMT) complex composed at least of RBBP5, ASH2L, SET1, SET2 and KMT2A/MLL1, KMT2D/MLL2, KMT2C/MLL3 and KMT2B/MLL4 through direct interaction with WDR5 (By similarity).
Similarity: Belongs to the GCF family.
Subunit Structure: Interacts with PAX3 and PAX7. Interacts with WDR5; associates with a histone methyltransferase (HMT) complex composed at least of RBBP5, ASH2L, SET1, SET2 and KMT2A/MLL1, KMT2D/MLL2, KMT2C/MLL3 and KMT2B/MLL4 through direct interaction with WDR5 (By similarity).
Similarity: Belongs to the GCF family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 105 kDa
Predicted: 105 kDa
Predicted: 105 kDa
NCBI Official Full Name
PAX3- and PAX7-binding protein 1 isoform 2
NCBI Official Synonym Full Names
PAX3 and PAX7 binding protein 1
NCBI Official Symbol
PAXBP1
NCBI Official Synonym Symbols
GCFC; BM020; GCFC1; FSAP105; C21orf66
NCBI Protein Information
PAX3- and PAX7-binding protein 1
UniProt Protein Name
PAX3- and PAX7-binding protein 1
UniProt Gene Name
PAXBP1
UniProt Synonym Gene Names
C21orf66; GCFC; GCFC1
NCBI Description
This gene encodes a protein that may bind to GC-rich DNA sequences, which suggests its involvement in the regulation of transcription. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2009]
Uniprot Description
Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of 'Lys-4' of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20 ().
Research Articles on GCFC1
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Product Notes
The GCFC1 paxbp1 (Catalog #AAA9609846) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GCFC1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GCFC1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the GCFC1 paxbp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GCFC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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