Human Wingless-Type MMTV Integration Site Family, Member 7A ELISA Kit | Wnt7a elisa kit

Human Wingless-Type MMTV Integration Site Family, Member 7A ELISA Kit

Cat. Num. AAA3804967

• Gene Names: Wnt7a; px; tw; Wnt-7a; AI849442
• Reactivity: Human
• Synonyms: Wingless-Type MMTV Integration Site Family; Member 7A; Human Wingless-Type MMTV Integration Site Family; Member 7A ELISA Kit; Wnt7a elisa kit

• Reactivity: Human
• Sequence Length: 349

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 125 pg/ml-2000 pg/ml
• Sensitivity: 10 pg/ml

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for Wnt7a elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofWINGLESS TYPE MMTV INTEGRATION SITE FAMILY, MEMBER 7Ain the sample, This WINGLESS TYPE MMTV INTEGRATION SITE FAMILY, MEMBER 7AELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusWINGLESS TYPE MMTV INTEGRATION SITE FAMILY, MEMBER 7Aconcentration. The concentration ofWINGLESS TYPE MMTV INTEGRATION SITE FAMILY, MEMBER 7Ain the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 31543960
• NCBI GeneID: 22421
• NCBI Accession #: NP_033553.2
• NCBI GenBank Nucleotide #: NP_033553.2
• UniProt Accession #: P24383
• NCBI Official Full Name: protein Wnt-7a isoform 1
• NCBI Official Synonym Full Names: wingless-type MMTV integration site family, member 7A
• NCBI Official Symbol: Wnt7a
• NCBI Official Synonym Symbols: px; tw; Wnt-7a; AI849442
• NCBI Protein Information: protein Wnt-7a
• UniProt Protein Name: Protein Wnt-7a
• UniProt Gene Name: Wnt7a
• UniProt Synonym Gene Names: Wnt-7a
• UniProt Entry Name: WNT7A_MOUSE

Uniprot Description

WNT7A: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts. Defects in WNT7A are the cause of limb pelvis hypoplasia aplasia syndrome (LPHAS). A syndrome of severe deficiency of the extremities due to hypo- or aplasia of one or more long bones of one or more limbs. Pelvic manifestations include hip dislocation, hypoplastic iliac bone and aplastic pubic bones. Thoracic deformity, unusual facies and genitourinary anomalies can be present. Defects in WNT7A are a cause of Fuhrmann syndrome (FUHRS); also known as fibular aplasia or hypoplasia femoral bowing and poly- syn- and oligodactyly. Fuhrmann syndrome is a distinct limb-malformation disorder characterized also by various degrees of limb aplasia/hypoplasia and joint dysplasia. Belongs to the Wnt family.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: proteinaceous extracellular matrix; extracellular space; cell surface; cell; extracellular region

Molecular Function: protein binding; frizzled binding; cytokine activity; receptor agonist activity; receptor binding

Biological Process: hindlimb morphogenesis; somatic stem cell maintenance; positive regulation of epithelial cell proliferation involved in wound healing; multicellular organismal development; positive regulation of transcription, DNA-dependent; Wnt receptor signaling pathway through beta-catenin; uterus development; cell-cell signaling; synapse organization and biogenesis; regulation of axon diameter; chondrocyte differentiation; somatic stem cell division; satellite cell activation; embryonic limb morphogenesis; cartilage condensation; cell fate commitment; skin morphogenesis; asymmetric protein localization; positive regulation of synaptogenesis; organ morphogenesis; response to estrogen stimulus; positive regulation of transcription from RNA polymerase II promoter; embryonic digit morphogenesis; negative regulation of apoptosis; embryonic forelimb morphogenesis; limb development; neurotransmitter secretion; cell proliferation in forebrain; positive regulation of JNK cascade; palate development; regulation of axonogenesis; signal transduction; embryonic hindlimb morphogenesis; negative regulation of neurogenesis; forelimb morphogenesis; central nervous system vasculogenesis; positive regulation of cell proliferation; angiogenesis; fallopian tube development; Wnt receptor signaling pathway; embryonic axis specification; satellite cell compartment self-renewal involved in skeletal muscle regeneration; cerebellar granule cell differentiation; regulation of cell proliferation; stem cell development; dorsal/ventral pattern formation; skeletal morphogenesis; establishment of cell polarity; cartilage development; reproductive structure development