Structure
MCB-613 Biochemical
MCB-613
Purity
>98% (HPLC)
Synonyms
MCB-613; MCB 613; MCB613; MCB-613 biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO: 50mg/mL (164.26mM)
H2O: <0.1mg/mL
H2O: <0.1mg/mL
Target
Hydroxylase
Receptor
Src
Chemical Name
(3E, 5E)-1-ethyl-3, 5-bis(pyridin-3-ylmethylene)piperidin-4-one
SMILES
C1(C/C(=Cc2cnccc2)/C(=O)/C(=C/c2cnccc2)/C1)CC
Molecular Formula
C20H20N2O
CAS Number
1162656-22-5
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for MCB-613 biochemical
MCB-613 is a potent Steroid Receptor Coactivator Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death. MCB-613 can super-stimulate SRCs' transcriptional activity. MCB-613 increases SRCs' interactions with other coactivators and markedly induces ER stress coupled to the generation of reactive oxygen species (ROS). MCB-613 selectively induce excessive stress in cancer cells. Over-stimulating the SRC oncogenic program can be an effective strategy to kill cancer cells. By integrating growth pathways on which cancer cells rely, steroid receptor coactivators (SRC-1, SRC-2, and SRC-3) represent emerging targets in cancer therapeutics.
Product Categories/Family for MCB-613 biochemical
References
1. Wang L, et al. Cancer Cell. 2015, 28 (2), 240-252.
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Product Notes
The MCB-613 (Catalog #AAA3607155) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MCB-613, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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