Structure
BIBO 3304 Biochemical
BIBO 3304
Purity
>98% (HPLC)
Synonyms
BIBO 3304; BIBO3304; BIBO 3304 biochemical
Purity/Purification
>98% (HPLC)
Target
Neuropeptide Y Receptor
Receptor
Neuropeptide Y Receptor
Chemical Name
(R)-2-(2, 2-diphenylacetamido)-5-guanidino-N-(4-(ureidomethyl)benzyl)pentanamide 2, 2, 2-trifluoroacetate
SMILES
C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC(CCCN=C(N)N)C(=O)NCC3=CC=C(C=C3)CNC(=O)N
Molecular Formula
C31H36F3N7O5
CAS Number
191868-14-1
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for BIBO 3304 biochemical
BIBO 3304 is a potent, selective, nonpeptide neuropeptide Y Y1 receptor antagonist with IC50 of 0.38 and 0.72nM for human and the rat Y1 receptor, respectively; shows low affinity for the human Y2 receptor, human and rat Y4 receptor, human and rat Y5 receptor (IC50>1,000nM); inhibits the feeding response induced by 1mg NPY in mice, also completely abolishes PYY-induced inhibition of insulin release in vivo. Obesity Discontinued
Product Categories/Family for BIBO 3304 biochemical
References
1. Wieland HA, et al. Br J Pharmacol. 1998 Oct; 125 (3):549-55.
2. Capurro D, et al. Eur J Pharmacol. 1999 Jul 9; 376 (3):251-5.
3. Loh K, et al. Nat Commun. 2017 Sep 8; 8 (1):490.
4. Kask A, et al. Neuropharmacology. 2000 Apr 27; 39 (7):1292-302.
2. Capurro D, et al. Eur J Pharmacol. 1999 Jul 9; 376 (3):251-5.
3. Loh K, et al. Nat Commun. 2017 Sep 8; 8 (1):490.
4. Kask A, et al. Neuropharmacology. 2000 Apr 27; 39 (7):1292-302.
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Product Notes
The BIBO 3304 (Catalog #AAA3603008) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "BIBO 3304, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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