Structure
CGP60474, Inhibitor
CGP60474
Purity
>98% (HPLC)
Synonyms
CGP60474; CGP-60474; CGP 60474; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
10mM in DMSO
Target
PKC
Receptor
PKC
Chemical Name
1-Propanol, 3-[[4-[2-[(3-chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]
SMILES
OCCCNC1=NC=CC(C2=NC(NC3=CC=CC(Cl)=C3)=NC=C2)=C1
Molecular Formula
C18H18ClN5O
CAS Number
164658-13-3
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for CGP60474, inhibitor
A potent CDK1 inhibitor with IC50 of 17nM; exhibits lower potency at CDK2 (IC50=50-80nM) and moderate potency at CDK4 (IC50=700nM).
Product Categories/Family for CGP60474, inhibitor
References
1. Ruetz S, et al. Curr Med Chem Anticancer Agents. 2003 Jan; 3 (1):1-14.
2. Kuo GH, et al. J Med Chem. 2005 Jul 14; 48 (14):4535-46.
2. Kuo GH, et al. J Med Chem. 2005 Jul 14; 48 (14):4535-46.
Similar Products
Product Notes
The CGP60474 (Catalog #AAA3602513) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CGP60474, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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