Western Blot (WB)
(Host: RabbitTarget Name: C1QBSample Tissue: Mouse Pancreas lysatesAntibody Dilution: 1ug/ml)
Rabbit anti-Mouse C1QB Polyclonal Antibody | anti-C1QB antibody
C1QB Antibody-middle region
Western Blot (WB)
(Host: RabbitTarget Name: C1QBSample Tissue: Mouse Pancreas lysatesAntibody Dilution: 1ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: C1QBSample Tissue: Mouse Pancreas lysatesAntibody Dilution: 1ug/ml)
NCBI and Uniprot Product Information
Uniprot Description
C1QB: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. Defects in C1QB are a cause of complement component C1q deficiency (C1QD). A rare defect resulting in C1 deficiency and impaired activation of the complement classical pathway. C1 deficiency generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis.
Protein type: Secreted; Secreted, signal peptide
Cellular Component: collagen; extracellular region; complement component C1 complex
Molecular Function: protein homodimerization activity
Biological Process: immune system process; innate immune response; inner ear development; complement activation, classical pathway
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Product Notes
The C1QB c1qb (Catalog #AAA3249731) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The C1QB Antibody-middle region reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's C1QB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the C1QB c1qb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: INSPLRPNQV IRFEKVITNA NENYEPRNGK FTCKVPGLYY FTYHASSRGN. It is sometimes possible for the material contained within the vial of "C1QB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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